Lec 19: Toxicology

Question 1

what is toxicology

Question 2

t/f : synthetic chemicals always worse than natural

Question 3

contrast poison and water hemlocks

Question 4

how do poison hemlocks act

Question 5

how do water hemlockls act

Question 6

contrast toxin vs toxicant

Question 7

what does tox assess and estimate

Question 8

classifications of tox

Question 9

goals of tox

Question 10

roles of toxicologists

Question 11

3 ways to chracterize tox risks

Question 12

how to identify hazards (ie what sources of data)

Question 13

what are the two mechs of toxicity

Question 14

what are common routes of tox exposure

Question 15

contrast acute and chronic exposure

Question 16

challenges with exposure assessment

Question 17

animal stdies: how to expoe them dep on what youre trying to test

Question 18

what is biomagnification

Question 19

what is dose response assessment

Question 20

contrast graded and quantal dose response curves

Question 21

what does ed 50 represent in graded dose response curves

Question 22

what does ld 50 measure in quantal doe reponse curves

Question 23

why do stdies assume a threshold response? what does this mean/

Question 24

what is the therapeutic index/ window?

Question 25

how to make extrapolations to assess chemical saftey

Question 26

what factors affect toxicity