Lec 21: rewards and substance use Flashcards
four pillars on the spectrum of psychoactive substance use. compare and contrast each
what is sud
what things play a role in sud
how do drugs become misused
what are the two theories of sud
explain the dopamine reqard system
what is dopamine? what does it play a role in? how does it go to receptors?
what is the reward system
what is the unstimulated conditon of the reward system
opioid and cocaine effect of the reward system
what do all misused substances have in common wrt effect on da neuron
cocaine on the rewards pathway
effect of opioids in the body? mech of misuse?
disinhibtion effect of cocaine?
how does compulsion occur>
dif between dependance and withdrawal
what is aquired tolerance
how does dependance occur with opioids
what happens with repeat exposure of opioids
how can you measure pd cellular tolerence
what is cellular tolerance
differences between cellular and metabolic tolerance
what is metabolic tolerances affect on dose response cruve
relationship between cellular tol and dep
how do ppl deal with tolerance/
how can dep lead to misuse of drugs?
different rates of effects: why does this affect dep
contrats dependance and craving
physiologically dependent on a drug ppl will do what
why are opioid deaths increasing
equipotent doses of morphine heroin dentanyl carfentanil
symptoms of opioid overdose
treatements for opioid overdose
what does a narcan / naloxone kit do
how is naloxone administered
pharm vs physio drug ints. examples?
interventions for sud
ways to support sud
pharmacotherapy for sud
