lec 2 Pericardium and myocardium pathology Flashcards
Etiology of Pericarditis
Primary causes is uncommon
Secondary causes more common
Primary causes of Pericarditis
Viral infection (often with concurrent myocarditis). – Bacteria – Fungi less common – Parasites
the most common systemic disorder
associated with pericarditis.
Uremia
Secondary causes of Pericarditis
– Acute MI or cardiac surgery (so-called “Dressler’s syndrome”),
– radiation to the mediastinum,
– processes involving other thoracic structures (e.g., pneumonia or pleuritis).
– Rheumatic fever
– Systemic lupus erythematosus Less common
– metastatic malignancies.
Pericarditis Sequalea
Resolve smoothly Large effusion (cardiac tamponade) Chronic pericarditis (fibrosis)
Morphology of Pericarditis
Fibrinous “bread and butter”
Fibrinopurulent (suppurative)
Fibrinous exudate and bloody effusion
Fibrinous exudate and bloody effusion result from
Metastases
Fibrinous “bread and butter result from
- Uremia, viral
* Mostly resolve spontaneously
Fibrinopurulent (suppurative)
• Acute bacterial • Caseaous in cases of tuberceulous pericarditis. • Mostly resolve spontaneously • But if extensive cause fibrosis