lec 2 Cardiac tumors

Question 1

The most common primary malignant

tumor in heart is

Answer 1

angiosarcoma

Question 2

The most common primary tumor of the heart in adult

Answer 2

Myxoma

Question 3

The most common primary tumor of the heart in children

Answer 3

Rhabdomyoma

Question 4

Primary tumors in order of frequency

Answer 4

• Myxomas ↓
• Fibromas ↓
• Lipomas ↓
• Papillary fibroelastomas ↓
• Rhabdomyomas ↓

Question 5

CARDIAC TUMORS classification

Answer 5

Primary Uncommon 80-90% are benign
, 10 % malignant
Secondary More common

Question 6

Secondary CARDIAC TUMORS Rout of spread

Answer 6

lymphatic extension, hematogenous seeding , direct contiguous extension, venous extension

Question 7

Myxomas 90% occurs in

Answer 7

atrium mainly in left atrium

Question 8

Myxomas arising in the region of the

Answer 8

fossa ovalis(atrial septum).

Question 9

MORPHOLOGY of Myxomas

Answer 9

Almost always single soft, translucent, villous lesions with a gelatinous appearance.

Question 10

Myxomas shape

Answer 10

sessile or pedunculated masses

Question 11

Myxomas effect

Answer 11

intermittent obstruction and “wrecking ball” effect that damages the valve leaflets

Question 12

Myxomas histology

Answer 12

myxoma cells
endothelial, smooth muscle, fibroblast
differentiation
acid mucopolysaccharide ground substance

Question 13

myxoma cells

Answer 13

stellate,

multinucleated)

Question 14

Rhabdomyoma most characteristic

cells are

Answer 14

“spider cells”

Question 15

Rhabdomyoma وين بتطلع

Answer 15

ventricular chambers

gray-white masses

Question 16

Rhabdomyoma

Answer 16

large, rounded, or polygonal cells containing numerous glycogenladen vacuoles separated by strands of cytoplasm running from
the plasma membrane to the centrally located nucleus, so-called
“spider cells”