LEC 2 Flashcards

1
Q

3 ways to classify motor neuron type

A
  1. How long to peak - larger mot = faster
  2. size of peak - larger = bigger
  3. how long to half of peak - larger = faster recovery
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2
Q

Name of electrode that is put into body via needle to measure specific deeper muscles

A

indwelling

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3
Q

Describe Heneman’s size principle

A

the orderly recruitment of smaller neurons before larger ones, same but in reverse for de-recruitment.

  • muscle fibre type also correlate to size of neuron e.g. SO fibres usually with smaller neurons etc.
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4
Q

contrast:

  • motor neuron pool
  • Motor unit
  • muscle unit
A

Motor neuron pool - all the motor neurons innervating a particular muscle

Motor unit - cell body and dendrites of a motor neuron, branches of its axon, and the muscle fibres it innervates

Muscle unit - all muscle fibres belonging to a motor unit

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5
Q

how do muscle units look within the muscle

A

muscle fibres are spread out, not grouped together

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6
Q

What is the innervation ratio, which muscles have high and low innervation ratio

what happens with aging

A

of muscle fibres innervated by a single motor neuron

eye have low

quad have high

with aging, ratio change (lose motor units, get higher ratios

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7
Q

in spinal cord, where are motor neurons for proximal and distal limbs located

A

proximal are more proximalo to the spinal cord, distal are more distal in the cord

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8
Q

what are the types of motor units that correspond to different muscle fibre types

A

Slow oxidative - connect to type I

Fatigue resistant - connect to fast oxidative-glycolytic fibres

Fast fatiguable - connect to fast glycolytic fibres

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9
Q

describe input resistance for small and large neurons

A

V=IR

High input resistance for smaller neurons means lower voltage needed to excite

Low input resistance for larger neurons make harder to excite

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10
Q

What is rheobase

A

measure of current that must be put into neuron to get it to fire.

Low rheobase in small motor neurons

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11
Q

which size neuron has a faster conduction velocity

A

Larger have faster conduction velocity

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12
Q

Which size neuron has a longer afterhyperpolarization phase

A

smaller have longer

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13
Q

What happens if you attach a slow motor neuron to a fast muscle fibre

A

it changes behaviour slightly to match motor neuron

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