Lec 1 Flashcards
What is Science?
“Systematic study of the structure and behavior of the physical and natural world through observation and experimentation”
Science is based on experimentation and observation of _________________
Natural phenomena
Science is based on _____________ - hypotheses that can be shown to be NOT TRUE based on data
Falsifiable hypotheses
What explanations for phenomena are beyond the scope of science?
Supernatural or faith-based explanations
Why is it incorrect to say it’s “Just a Theory”?
Scientific theories must be based on supported hypotheses (facts)
Scientific theories must be falsifiable
Scientific theories are the most reliable, rigorous, and comprehensive form of scientific knowledge
Scientific theories are built on MOUNTAINS of theory and MUST be falsifiable; VERY rigorous
Theory vs. scientific theory
Theories are generalized explanations of how things work
Scientific theories are built on mountains of data
An hypothesis is:
A testable idea
Theory
In every day life, it’s used as “opinion, hunch, or guess”
Scientific Theory
Supported by many facts; must be supported by multiple tests
Scientific Law
NOT the same as Scientific Theory
Theory explains the why, Law explains the WHAT
Well-known scientific theories
Theory of Earth Rotation (1613)
Theory of Blood Circulation (1628)
Theory of Gravity (1687)
Cell Theory (1839) [1891*]
Germ Theory of Disease (1020*) (1856)
Theory of Evolution (1859)
Theory of Plate Tectonics (1920)
Theory of Relativity (1920)
Evolutionary Theory
1859
General explanation for biodiversity on earth supported by evidence
Origins and Development of Evolutionary Theory
Darwin was not the first to propose the idea that species can change through time
His Theory of Descent with Modification by Natural Selection was hugely influential in the development of the modern Theory of Evolution
What is evolution?
Evolution is change over time… specifically the change in ALLELE frequencies over time
Darwin did not initially describe evolution as changes in allele frequencies. He conceptualized it as changes in phenotype - the outward appearance of an organism.
Evolution is the foundation of out understanding of __________
ALL biological processes
“Nothing in biology makes sense except in the light of _______” - ________
Evoltuion
Theodosius Dobzhansky
Scientific Questions asked by pre-Darwinian thinkers
What separates science and mythology?
How should scientists draw conclusions about the natural world?
How does the natural world change?
Why is the world filled with a diversity of life forms?
Where do species come from?
Why are organisms so well-suited to their environments?
Methodological Naturalism
Every human culture has creation myths to explain how the wordl came to be
Greek philosophers such as Anaximander (610-546 BC) attempted to develop ideas of a natural world driven by physical laws
These were driven by PHYSICAL LAWS
Methodological Naturalism: Anaximander’s Cosmology
The heavenly bodies (planets) are not divine
Suggested that the sun, moon, and stars are physical objects
Stated that heavenly bodies rotate around the earth (not true)
Set the stage for natural, rather than supernatural, explanations for phenomena
Power of Methodological Naturalism
Natural explanations for natural processes are testable, because we can observe and manipulate these processes
Supernatural explanation are not testable because supernatural causation cannot be observed or manipulated
We call it “methodological” because it provides a method for seeking scientific explanations of the world
These features separate science from mythology
Hypothesis Testing
Aristotle (384-322 BC) introduced the idea of HYPOTHESIS TESTING
This means principles must agree with facts - not the other way around
We should be able to observe and manipulate the processes underlying out hypotheses
In facts and principles do not agree, we must re-evaluate our principles
Principles MUST agree with facts; if a fact contradicts a principle, you change the hypothesis, NOT the fact
Basis of Hypothesis Testing
- Scientific hypotheses require causal explanations and must be rigorous
- Scientific hypotheses must be falsifiable; must be able to show that they are not true
- Hypothesis testing requires a control
- Hypothesis testing must be repeatable
If we can’t get the same results in other tests, it is not a good hypothesis
A hypothesis is a _______ based on the knowledge obtained while formulating a question
Conjecture
Control
Un-manipulated condition
Origins of the scientific process
Testing hypotheses and the application of natural and mathematical laws and logic allow thinkers to move from facts to general principles
Ibn al-Haytham (965-1040AD), an Arab mathematician and philosopher, is often considered the first to employ systematic approach to varying experimental conditions in his studies of optics
Classic test of hypotheses about origin of life
Ideas of spontaneous generation of life existed in the ancient world and persisted for thousands of years
Francesco Redi used a modern experiment to test this idea in 1668
Hypothesis: Flies generate spontaneously in meat
Predictions: If hypothesis supported, there should be flies in all treatment jars
There was an idea that flies spontaneously generate out of meat because any time a piece of meat is out, flies appear on it quickly
Flies only appeared in open containers, maggots, too
Which of these is NOT a testable, falsifiable hypothesis?
a) The disease COVID-19 is caused by the coronavirus SARS-CoV-2
b) Transmission of the SARS-CoV-2 virus occurs primarily through respiratory droplets
c) The COVID-19 pandemic is punishment for human destruction of the environment
d) The SARS-CoV-2 virus emerged from a single transmission from animals to humans, rather than many transmission events
The COVID-19 pandemic is punishment for human destruction of the environment
We cannot test the “idea” that the pandemic is punishment of any sort; can’t collect data that can falsify this idea
Early ideas about Evolution can be tracked to 3 philosophers
Anaximander (611-547 BC), Empedocles (492-432 BC) and Lucretius (99-55 BC) proposed that all living things were related and that they had changed over time
Who demonstrated that things change over time?
Aristotle in his Scala Naturae explained the advancement of living things from inanimate matter to plants, then animals and finally man
It was thousands of years before these ideas were widely accepted
Early ideas about Evolution
Zhuangzi (circa 300 BC) proposed that life forms have an innate ability to transform and adapt to their surroundings
he also indicated that humans are subject to this process
Al-Jahiz (781-869)
Arab scholar interested in natural history proposed the first modern theory of evolution in the Book of Animals
Largely ignored by the western world, but possibly inspired Darwin
Al-Jahiz’s Theory of Evolution
Animals engage in a struggle for existence, for resources, to avoid being eaten and to breed
-Many of these ideas are similar to MARKIAN evolution
Environmental factors influence organisms to develop new characteristics to ensure survival, thus transforming into new species
Animals that survive to breed can pass on their successful characteristics to offspring
Early ideas about evolution: Avicenna
980-1037
Persian scholar and philosopher
One of the most important scientists in history - discovered the nature of infection diseases
Proposed for the first time the Law of Superposition: Older layers of sediment are covered by younger layers
Law of Superposition
Older layers of sediment are covered by younger layers
Helps us determine AGE of earth
Can age sediment based on how deep they are
Setting the stage for evolutionary theory: gradual change over time
Early thinkers assumed the earth was young
Leonardo da Vinci (1452 - 1519) calculated the sedimentation rates in the Po River of Italy, and concluded it took 200,000 years to form some nearby rock deposits
-Using superposition to age it, lower layers will be older than layers higher up in rock
Setting the stage for evolutionary theory: Uniformitarianism (gradual change over time)
First proposed by George-Louis Leclerc, James Hutton and refined by Charles Lyell in the 1800’s
Basis of Uniformitarianism
Idea that slow acting processes over long periods of time can produce dramatic results
Contrasted with prevailing view of “catastrophism”
Catastrphism
Geological features emerge from major, catastrophic events
i.e. the Grand Canyon formed by SLOW PROCESSES, not catastrophe
Uniformitarianism
Important because accepting gradual change means that these changes are observable and could be tested experimentally
Difficult to observe, measure, and manipulate changes that occur due to unpredictable natural catastrophes
Setting the stage for evolutionary theory: The struggle for existence
Erasmus Darwin (1731-1802), grandfather of Charles Darwin, discussed the notion of a STRUGGLE FOR EXISTENCE:
- Organisms are in a constant struggle to obtain resources and use those resources to produce offspring
- Humans descended form another primate
- Failed to connect struggle for existence to evolutionary change over time
Even though he observed competition, he did NOT see the struggle for existence as a driver for evolution (couldn’t prove this hypothesis)
Setting the stage for evolutionary theory: Species change through time
Robert Chambers (1802-1871) in his Vestiges of the Natural History of Creation highlighted two critical points about the fossil record:
- The species composition changed through time
- -You don’t find identical species in different layers; in history, there has been some change in the species present on earth
- This change is slow, gradual and unlinked to catastrophes
- -Support for Uniformitarianism
Hypothesized new species arise from old species
Did not explain WHY new species arise (answered by Charles Darwin)
Setting the stage for evolutionary theory: Organisms are well-suited to their environments
William Paley (1743-1805) in his Natural Theology discussed the metaphor of the Watchmaker
Organisms are like watches, if one piece is absent of misplaced the watch will fail to function
Recognized that organisms were well-suited to their environments
He assumed a supernatural creator must have put them together; NOT a testable hypothesis
Setting the stage for evolutionary theory: Adaptation
Jean-Baptiste Lamarck (1744-1829) in his Zoological Philosophy proposed this Theory of Adaptation
More complex species descend gradually from older, less complex species
This occurs through a process of adaptation, in which organisms acquire new traits during their lifetimes
Formation of complex from more simple due to adaptation
Lamarck: Inheritance of acquired characteristics
Hypothesized that an organism can acquire characteristics during its lifetime and pass them on to its offspring
-The long legs of shorebirds are the results of birds stretching their legs to avoid sinking in the mud
Connected PHENOTYPE ot environment
Idea: giraffes got long necks to reach leaves on tops of trees, passed on to offspring
This is INCORRECT, but this is the first time that a phenotype was connected to the environment
Phenotype - Lamarck
Key Vocabulary: Phenotype
The outward appearance of an organism
Setting the stage for evolutionary theory: More individuals are produced than can survive
Robert Malthus (1766-1834) argued that humans would outstrip the available resources necessary to sustain themselves, leading to population growth that would be checked by famine, war, and disease
Malthus came up with the idea that more individuals are produced than can survive Malthus was not a scientist
Applies to natural populations: Food supply is constant and population growth tends to be exponential
When resources are limited, the best suited organisms obtain more resources than the rest