learning/memory Flashcards

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1
Q

Describe learning

A
  • adaptive change in behavior produced by some event or experience
  • involves acquisition and storage (consolidation)
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2
Q

describe memory

A
  • Stored record of the interpreted experience or some aspect thereof
  • involves a wide array of neuronal circuits and a process for activation (recall)
  • cataloguing (codification = the process whereby information is stored in some context
  • cross referencing = same info is stored in various “catalogues” enabling access to the info via different routes (contexts)
  • Memory trace or engram = the pathway or pattern of activity of a neuronal circuit unique to the record (memory)
  • memories can exist at all levels of the neuraxis (reflexes, names, faces, skilled behaviors)
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3
Q

Declarative (explicity)

A
  • FACTS AND EVENTS
  • Medial temporal lobe (hippocampus and surrounding structures) and Diencephalon (basal forebrain, thalamus)
  • Can be brought to conscious level and described or examined
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4
Q

Non-declarative (implicit, procedural)

A
  • Skilled movements and habits (motor behavior)–> striatum, motor cortex, cerebellum, spinal reflex circuits
  • Priming (process of completing a word/picture when only presented iwth a portion of the info (based upon prior experience) –> neocortex
  • Basic associative learning (emotional responses = amygdala; Skeletal musculature = cerebellum, spinal reflex circuity)
  • Non-assocaitive learning = complex reflexive pathways
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5
Q

describe associative learning

A
  • relationship between two or more stimuli
  • Passive = simple conditioning, temporal relation between stimuli (pavlov’s dog)
  • Operant
  • -> stimulus is associated with a diferent reinforcement stimulus
  • -> reinforcement stimulus may be positive or negative
  • -> Positive reinforcement will enhance the ocurrence of behavior
  • -> negative reinforcement will enhance a behavior to avoid an undersirable condition
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6
Q

Non-associative (simple) learning

A
  • habituation (tolerance) = diminished response following a repeated stimuli
  • Sensitization = enhancement of a response by the addition of a second strong of noxious stimuli
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7
Q

Non-associated (complex) learning

A
  • Imprinting = bonding or behavioral attraction of a young animal to a parent (developmental process which much occur during a critical period)
  • Vicarious or latent
  • -> simple experience of familiarity
  • -> no motivation or reinforcement (reward)
  • -> imitation or observation
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8
Q

describe reverberating circuits for learning

A
  • SHORT TIME PERIOD
  • requires continuous neuronal activity
  • rapid extinction, new info replaces old
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9
Q

long term potentiation

A
  • defined stimulus to the afferent pathway of the hippocampus will produce a characteristic and reproducible response
  • NO thought to play an important role (is long-lived, but only lasts a defined period; maintenance requires further metabolic changes)
  • LPT mediates a process of encoding memories in the hippocampus and other areas
  • in similar process long-term depression also seems to be a process for encoding memories (could be process for undoing LTP
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10
Q

Anterograde amnesia

A
  • inability to form NEW memories
  • -> defect in consolidation
  • -> hippocampal damage (left-verbal; right - nonverbal)
  • -> affects declarative and not procedural memory
  • -> may be induced by anesthetics and sedative hypnotics
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11
Q

retrograde amnesia

A
  • inability to RECALL previously stored memories
  • -> temporal quality = older memories more resistant, newer memoreis more vulnerable
  • -> defect in RECALL
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12
Q

agnosia

A

= inability to recognize various stimuli/forget what they mean
–> visual, auditory or tactile

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13
Q

alzheimers disease

A
  • Most common form of cortical dementia in humans
  • symptoms include aphasia, apraxia, agnosia and anterograde amnesia
  • Characterized by neurofibrilary triangles and senile (beta-amyloid) plaques throughout the cortex and forebrain structures
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