Learning Guide Questions Flashcards
T or F
Reiters Syndrome is most common in elderly women
F
T or F
Reiters Syndrome response promptly to antimicrobials
F
T or G
Reiters syndrome is associated with retinitis
F
T or F
Reiters syndrome may follow Shigella
T
T or F
Reiter Syndrome is a self limiting illness <6 weeks duration
F
T or F
Aminoglycoside Abx such as gentamicin may be administered once daily
T
T or F
Aminoglycoside Abx such as gentamicin have synergistic activity with penicillins against enterococci
T
T or F
Aminoglycoside Abx such as gentamicin are effective in the Rx of severe pneumococcal pneumonia
F
T or F
Aminoglycoside Abx such as gentamicin may cause loss of healing in the elderly
T
T or F
Aminoglycoside Abx such as gentamicin should not be given to patients with severe renal impairment
F
T or F
Useful drugs in fungal infections are:
Zidovudine
F
T or F
Useful drugs in fungal infections are:
Netilmicin
F
T or F
Useful drugs in fungal infections are:
Itraconazole
T
T or F
Useful drugs in fungal infections are:
Nystatin
T
T or F
Useful drugs in fungal infections are:
Amphotericin B
T
T or F Varicella Zoster Virus (VZV):
May cause haemorrhage shingles in the immunocompromised
T
T or F Varicella Zoster Virus (VZV):
Is characterised by a discrete macular rash
F
T or F Varicella Zoster Virus (VZV):
Can be followed by neuralgia
T
T or F Varicella Zoster Virus (VZV):
Is a cause of severe pneumonia
T
T or F Varicella Zoster Virus (VZV):
Is not sensitive to existing antivirals
F
T or F Pyrexia of unknown origin:
Is a definition applied to any unDx fever >24hrs
F
T or F Pyrexia of unknown origin
May be a features of cranial arteritis
T
T or F Pyrexia of unknown origin
Is most frequently caused by viral infections
F
T or F Pyrexia of unknown origin may be a feature of military TB
T
T or F Pyrexia of unknown origin may be the presenting feature of lymphoma
T
T or F In malarie due to Plasmodium Vivax symptoms always develop within 1 months of returning from an endemic area
F
T or F In malarie due to Plasmodium Vivax cerebral malaria is always recognised as a complication
F
T or F In malarie due to Plasmodium Vivax infection is often acquired in the Indian Subcontinent
T
T or F In malarie due to Plasmodium Vivax Thrombocytopenia is a recognised feature
T
T or F In malarie due to Plasmodium Vivax resistance to antimalarials is common
F
T or F in HIV infection
Acute seroconversion may be associated with rash and diarrhoea
T
T or F in HIV infection
Disease progress associated with a decline in CD4 lymphocytes
T
T or F in HIV infection
Antiviral treatment is best started with single agent
F
3 agents
T or F in HIV infection
Symptoms always develop within 5 yrs of infection
F
T or F in HIV infection Disease progresses most rapidly in patients infected through homosexual contact
F
T or F
In campylobacter enteritis symptoms start within 24hrs
F
T or F
In campylobacter enteritis antibiotic treatment is usually indicated
F
T or F
In campylobacter enteritis Positive blood cultures are found in 10% patients
F
T or F
In campylobacter enteritis Dx is confirmed by stool culture
T
T or F
In campylobacter enteritis Guillian Barre syndrome is a recognised complication following infection
T
T or F
In pseudomembranous colitis characteristic lesions are seen on colonoscopic biopsy
T
T or F
In pseudomembranous colitis positive cultures for clostridium difficult are found in 50% patients
F
T or F
In pseudomembranous colitis the Dx can be made by detection of C diff toxin in the stool
T
C diff cannot be cultured though must be the toxin
T or F
In pseudomembranous colitis a history of Abx consumption in the previous 6 weeks is usually ellicted
T
T or F
In pseudomembranous colitis oral metronidazole often proves effective treatment
T
metronidazole
T or F Lyme disease:
Is caused by Borrelia Burgdoferi
T
T or F Lyme disease:
Is spread by rat fleas
F
T or F Lyme Disease: May be associated with cranial nerve palsies
T
T or F Lyme disease does not response to B lactam Abx:
F
T or F Lyme disease is Dx on serological test:
T
Select the most appropriate Dx or causative organism:
a) Clostridium dif cile
b) Superantigen induced toxic shock syndrome
c) Septic shock
d) MRSA
e) E.coli 0157
f) Listeria monocytogenes
g) Pneumococcal meningitis
h) Strep. pyogenes
i) Meningococcal sepsis
j) Group B streptococcus
17 years old girl who suddenly became drowsy, fevered and is developing a petechial rash
i. Meningococcal sepsis (petechial rash hallmark)
Select the most appropriate Dx or causative organism:
a) Clostridium dif cile
b) Superantigen induced toxic shock syndrome
c) Septic shock
d) MRSA
e) E.coli 0157
f) Listeria monocytogenes
g) Pneumococcal meningitis
h) Strep. pyogenes
i) Meningococcal sepsis
j) Group B streptococcus
54 years old man with Gram -ve bacilli seen on microscopy in 2 bottles of a blood cultures, is transferred to ITU because he has gone into renal failure and is hypotensive despite adequate fluid resuscitation
c. Septic shock (hypotension despite adequate fluid resuscitation, organ failure - suggesting sepsis)
Select the most appropriate Dx or causative organism:
a) Clostridium dif cile
b) Superantigen induced toxic shock syndrome
c) Septic shock
d) MRSA
e) E.coli 0157
f) Listeria monocytogenes
g) Pneumococcal meningitis
h) Strep. pyogenes
i) Meningococcal sepsis
j) Group B streptococcus
75 yr female treated for 5 days with co-amoxiclav for chest infection who has developed severe diarrhoea
a. Clostridium difficile (use of 1 of the 4 C abx.)
A 25 year old man presents with a three week history of breathlessness and dry cough. He had lost two stones in weight during the previous six months and was found to have generalised lymphadenopathy and oral candidiasis. A chest X-ray shows bilateral peri-hilar pulmonary in ltrates.
What is the most likely cause of this patients breathlessness and what disease underlies it?
Pneumocystis jirovecci pneumonia or PCP
AIDS or HIV disease.
A 25 year old man presents with a three week history of breathlessness and dry cough. He had lost two stones in weight during the previous six months and was found to have generalised lymphadenopathy and oral candidiasis. A chest X-ray shows bilateral peri-hilar pulmonary in ltrates.
How might you confirm the cause of his breathlessness
PCR confirmed by PCR of induced sputum or broncho-alveoli lavage
A 25 year old man presents with a three week history of breathlessness and dry cough. He had lost two stones in weight during the previous six months and was found to have generalised lymphadenopathy and oral candidiasis. A chest X-ray shows bilateral peri-hilar pulmonary in ltrates.
After the patient recovers from his acute illness what can be done to prevent a recurrence?
Prophylaxi with daily co-trimoxazole or monthly inhaled pentamidine
A 25 year old man presents with a three week history of breathlessness and dry cough. He had lost two stones in weight during the previous six months and was found to have generalised lymphadenopathy and oral candidiasis. A chest X-ray shows bilateral peri-hilar pulmonary in ltrates.
What treatment can be given for the underlying disease process and how can the effect of the treatment be monitored?
Combination anti-viral therapy
CD4 lymphocyte counts
Quantitive HIV viral load
Clinical response from the patient
A 25 year old man presents with a three week history of breathlessness and dry cough. He had lost two stones in weight during the previous six months and was found to have generalised lymphadenopathy and oral candidiasis. A chest X-ray shows bilateral peri-hilar pulmonary in ltrates.
One year later the patient presents with a visual field defect. Which opportunistic infection is the most likely cause
CMV (cytomegalovirus) - affects the brain in HIV/AIDS patients
