Learning and Memory Flashcards
Brain structure for primitive emotional and survival response~ such as fight or flight and feeding and mating
Hypothalamus
HIghest cognitive funcitons.. affords control over emotions
Frontal Cortex
Production and appreciation of art
Prefrontal cortex
Key for storage of emtional memories
Amygdala
Brain structure that provides episodic memory
Hippocampus
An overacted hypothalamus (during high stress situations) will inhibit the _______ and let the more primitive responses win out
frontal cortex
Key for judgment, decision making, morality, compassion and responsibility
Frontal cortex
when is the frontal cortex fully developed?
Not until age 20
The elephant art gallery displayed that elephants have a very large _______
Frontal cortex
motor control, spatial ability, emotion and memory
Prefrontal cortex
Amygdala will receive info from the _____ and send it back
frontal cortex
Necessary for us to remember the details of our lives
hippocampus
Storage of emotional memories—activated and inhibited by Emtionality
HIppocampus
HIppocampus is located very close to the
amygdala
for explicit, episodic or declaritive memory and highly susceptible to disrupt by stress
Hippocampus
- synaptic plasticity:
ability of synapses to change strength in response to expereince and a cellular model of learning and memory
Glutamatergic receptors:
________—basal synaptic transmission
AMPA receptors
______—blocked by Mg++ and activated when cells are depolarized. Important for synaptic plasticity
NMDA receptors
NMDA receptors—blocked by Mg++ and activated when _______. Important for synaptic plasticity
cells are depolarized
Ligand binding causes the AMPARs to open, and _____flows into the postsynaptic cell, resulting in a depolarization
Na+
NMDARs can open only when a
depolarization from the AMPAR activation leads to repulsion of the Mg2+ cation out into the extracellular space, allowing the pore to pass current.
NMDARs are permeable to
both Na+ and Ca2+
The Ca2+ that enters the cell triggers the upregulation of AMPARs to the membrane, which results in a
long-lasting increase in EPSP size underlying LTP.
The calcium entry though NMDA will _________, which phosphorylates AMPARs, increasing their single-channel conductance.
phosphorylates CaMKII