Learning and Memory Flashcards
What are the two types of amnesia
retrograde amnesia and anterograde amnesia
What is retrograde amnesia
difficulty retrieving memories before onset of amnesia
What is anterograde amnesia
inablity to form new memories
What is declarative memory
Brain area: Medial temporal lobe and hippocampus
facts and events
Episodic and semantic
What is episodic memory
remembering the first day of school
personal memory(events)
What is semantic memory
remembering the capital of America
general knowledge(Facts)
What is Non Declarative Memory
procedural memory skills and habits, classical conditioning, emotional responses
H.M.
hippocampus removed to cure severe epilepsy, normal short term memory, no new declarative long term memories, some retrograde amnesia, was still able to remember skills and habits
Mirror Star Trials
Trial 1= a lot of errors
Trial 2= fewer errors
Trial 3= little to no errors
shows he can learn skills without remembering that he did them
N.A.
Damage to dorsal medial Thalamus and mammillary bodies, retro and anterograde deficit in declarative memory
Korsakoff Alcoholics with thiamine defiency
difficulting with anterograde and retrograde amnesia, diseased dorsal medial thalamus and mammillary bodies
K.C.
Damage to left frontal-parietal ctx and right parietal occipital ctx, hippocampal area, no personal memory but had generalized knowledge
What are the similarities between Korsakoff and N.A.
They both have damage to the dorsal medial thalamus and mammillary bodies
What are the similarities between H.M. and K.C.
both have damage to the hippocampus
Which ones have non declarative memory but no declarative memory
H.M., N.A. and korsakoff
PKU
lack enzyme that breaks down phenylalamine
Down syndrome
caused from mother’s age, low IQ
Fragile X
abnormal number of Trineuleotide repeats, more in boys, causes autism
What causes memory impairment
hippocampal shrinkage from aging
Alzheimers
decline in cerebellar metabolism and intellect
Beta Amyloid placts
form the outside neurons, formed by the cutting of APP
Neuro fibrillary tangles
form inside neuron, has TAU protein
Loss of Basal Forebrain
Loss of ACH causes loss of learning and memory, leads to Alzheimer’s
What causes amyloplasts
APP cut by B-serctose and presiniline
What is priming
change in processing of a stimulus because of prior exposure
Memory has
temporal stages
What are sensory memories
reflects continuation of sensory(visual, sounds etc) neural activity, short, super short
How long do short term memories last
last seconds
How long do intermediate memories last
last seconds to minutes