Last Pointers Flashcards
1
Q
What anti-histamine tends to especially cause P450 inhibition?
A
Cimetidine
2
Q
What is the mechanism of resistance to Azithromycin?
A
Phosphorylation of 50S ribosome at P site.
3
Q
What is the mechanism of resistance to Fluoroquinolones?
A
Alteration on DNA gyrase/topoisomerase IV binding sites and enhanced efflux.
4
Q
What is the mechanism of resistance to Gentamycin and Tobramycin?
A
Decreased uptake
5
Q
What is the mechanism of resistance to Doxycycline?
A
Enhanced efflux
6
Q
What drug can be used to treat Onchomycoses?
A
Terbinafine
7
Q
What is Capsofungin used for?
A
Azole-resistant Candidiasis and Aspergillus