Last Pointers Flashcards

1
Q

What anti-histamine tends to especially cause P450 inhibition?

A

Cimetidine

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2
Q

What is the mechanism of resistance to Azithromycin?

A

Phosphorylation of 50S ribosome at P site.

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3
Q

What is the mechanism of resistance to Fluoroquinolones?

A

Alteration on DNA gyrase/topoisomerase IV binding sites and enhanced efflux.

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4
Q

What is the mechanism of resistance to Gentamycin and Tobramycin?

A

Decreased uptake

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5
Q

What is the mechanism of resistance to Doxycycline?

A

Enhanced efflux

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6
Q

What drug can be used to treat Onchomycoses?

A

Terbinafine

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7
Q

What is Capsofungin used for?

A

Azole-resistant Candidiasis and Aspergillus

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