LAst minute

Question 1

Ki67 or PCNA are indicators of what?

Answer 1

These are markers of tumor growth/proliferation.

Question 2

Bizzare giant multinucleated cells are a hallmark feature for what type of tumor?

Answer 2

Hallmark feature for anaplasic tumors.

Question 3

Expression of what on tumor cells will favor metastasis?

Answer 3

CD 44

Question 4

What type of cancer typically causes osteoblastomas?

Answer 4

Prostate cancer.

Question 5

What type of cancer will typically lead to Osteolytic metastasis?

Answer 5

PGE2 and IL-1 producing tumors.

Breast cancer will cause this as well.

Question 6

What is the metastatic site for Stomach adenocarcinoma?

Answer 6

Virchows left supraclavicular node

Question 7

What is the metastatic site for Renal adenocarcinoma?

Answer 7

Lung

Question 8

What is the metastatic site for lung carcinoma?

Answer 8

Adrenal/liver

Question 9

Which primary tumor commonly metastasizes to the brain?

Answer 9

LUBGOM
Lung
Breast
Genitourinary
Isteosarcoma
Melanoma
GI

Question 10

Which primary tumor commonly metastasizes to the liver?

Answer 10

Colon
Stomach
Pancrease

Question 11

What primary tumor will metastasize to the bone?

Answer 11

PRostate, breast, lung, thyroud.

Question 12

What is the Dukes system for staging?

Answer 12

Colorectal cancers

Question 13

What is the Ann Arbor System for staging?

Answer 13

Hodgkin and non hodgkin lymphomas.

Question 14

What does Nickel exposure put you at risk for?

Answer 14

Nose and lung cancer

Question 15

What does radon exposure put you at risk for?

Answer 15

Lung cancer

Question 16

What does vinyl chloride put you at risk for?

Answer 16

Angiosarcoma of the liver

Question 17

What does Aniline dies put you at risk for?

Answer 17

Bladder cancer sen in manufacturing of aniline dyes, textiles, and rubber work

Question 18

What neoplasm is associated with AIDS?

Answer 18

Malignant lymphoma

Kaposi Sarcoma

Question 19

What neoplasm is associated with Barret esophagus?

Answer 19

Esophageal adenocarcinoma

Question 20

What neoplasm is associated with chronic atrophic gastritis, pernicious anemia, postsurgical gastric remains?

Answer 20

Gastric adenocarcinoma

Question 21

What neoplasm is associated with Cushings syndrome?

Answer 21

Small cell lung cancer due to over expression of ACTH.

Question 22

What neoplasm is associated with Down syndrome?

Answer 22

ALL
and
AML

Question 23

What neoplasm is associated with Hypercalcemia?

Answer 23

Squamous cell lung cancer

Question 24

What neoplasm is associated with Polycthemia?

Answer 24

Renal cell carcinoma

Hepatocellular carcinoma

Question 25

What Neoplasm is associated with SIADH?

Answer 25

Small cell lung cancer

Question 26

What Neoplasm is associated with ulcerative colitis?

Answer 26

Colonic adenocarcinoma.

Question 27

What happens if Fibroblast growth factors (HST1) are over expressed?

Answer 27

Stomach cancer

Question 28

What happens if HGF is over expressed?

Answer 28

Thyroid cancer

Question 29

What happens if the receptor ERBB2 (HER-2/NEU) is over amplified?

Answer 29

Breast cancer | Ovarian Cancer

Question 30

What happens if the receptor for neutrophic factors (RET) receives a point mutation?

Answer 30

MEN 2A and 2B | Familial medulary thyroid carcinomas

Question 31

What happens if there is a point mutation in the KRAS gene?

Answer 31

Pancrease Colon Lung Cancer

Question 32

What happens if there is a translocation in the ABL ene?

Answer 32

Chronic myeloid leukemia | Acute lymphoblastic leukemia

Question 33

What happens if there is a point mutation or over expression of the B-catenin gene in WNT signalling?

Answer 33

Hepatoblastomas and | Hepatocellular carcinoma

Question 34

What happens if there is a translocation of the c-Myc gene?

Answer 34

Burkitt lymphoma

Question 35

What happens if there is an amplification of the N-myc gene?

Answer 35

Neuroblastoma | Small cell carcinoma of the lung

Question 36

What hapens if there is a translocation of the Cyclin D gene?

Answer 36

Mantle cell lymphoma

Question 37

What happens if there is an amplification of the Cyclin D gene?

Answer 37

Breast and esophageal cancer.