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Pharm 5 > Last exam drugs > Flashcards

Last exam drugs Flashcards

1
Q

Digoxin: drug group

A

Digitalis Glycoside

Positive Inotrope

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2
Q

Milrinone: drug group

A

Phosphodiesterase Inhibitor

Positive Inotrope

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3
Q

Dobutamine: drug group

A

Positive Inotrope

Adrenoceptor Agonist

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4
Q

ACEI: drug group

A

Angiotensin inhibitor

Vasodilator

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5
Q

ARB: drug group

A

Angiotensin Inhibitor

Vasodilator

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6
Q

Hydralazine: drug group

A

Vasodilator

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7
Q

Isosorbide Dinitrate: drug group

A

Vasodilator

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8
Q

Spironolactone: drug group

A

Aldosterone Antagonist

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9
Q

Eplerenone: drug group

A

Aldosterone Antagonist

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10
Q

Carvedilol: drug group

A

Beta adrenoreceptor blocker

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11
Q

Bisoprolol: drug group

A

Beta adrenoreceptor blocker

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12
Q

Metoprolol: drug group

A

Beta adrenoreceptor blocker

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13
Q

Furosemide: drug group

A

Loop diuretic

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14
Q

Bumetanide: drug group

A

loop diuretic

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15
Q

Torsemide: drug group

A

loop Diuretic

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16
Q

Ivabradine: drug group

A

Hyper polarization active cyclic nucleotide-gated channel blocker

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17
Q

Sacubitril/Valsartan (Entresto): drug group

A

Angiotensin receptor Neprilysin Inhibitor

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18
Q

Captopril: drug group

A

ACEI

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19
Q

Enalapril: drug group

A

ACEI

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20
Q

Fosinopril: drug group

A

ACEI

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21
Q

lisinopril: drug group

A

ACEI

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22
Q

quinapril: drug group

A

ACEI

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23
Q

ramipril: drug group

A

ACEI

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24
Q

tradolopril: drug group

A

ACEI

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25
Q

candesartan: drug group

A

ARB

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26
Q

losartan: drug group

A

ARB

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27
Q

valsartan: drug group

A

ARB

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28
Q

warfarin

A

vit K antagonist

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29
Q

heparin

A

indirect thrombin inhibitor

unfractionated heparin

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30
Q

Enoxaparin

A

indirect thrombin inhibitor

LMWH

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31
Q

dalteparin

A

indirect thrombin inhibitor

LMWH

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32
Q

tinzaparin

A

indirect thrombin inhibitor

LMWH

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33
Q

danaparoid

A

indirect thrombin inhibitor

LMWH

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34
Q

Fondaparinux

A

Factor X inhibitor

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35
Q

lepirudin

A

direct thrombin inhibitor

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36
Q

bivalirudin

A

direct thrombin inhibitor

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37
Q

dabigatran

A

direct thrombin inhibitor

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38
Q

rivaroxaban

A

active factor x inhibitor

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39
Q

apixaban

A

active factor x inhibitor

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40
Q

ASA (asprin)

A

antiplatelet drugs

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41
Q

clopidigrel (plavix)

A

antiplatelet drug

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42
Q

dipyridamole

A

antiplatelet drug

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43
Q

prasugrel

A

antiplatelet drug

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44
Q

ticlopidine

A

antiplatlet drug

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45
Q

abciximab

A

glycoprotein IIb/IIIa receptor antagonist

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46
Q

eptifibatide

A

glycoprotein IIb/IIIa receptor antagonist

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47
Q

tirofiban

A

glycoprotein IIb/IIIa receptor antagonist

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48
Q

protamine sulfate

A

reverses unfractionated heparin, LMWH (not as well)

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49
Q

vit K

A

reverses warfarin

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50
Q

fresh frozen plasma

A

reverses warfarin

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51
Q

argatroban

A

direct thrombin inhibitor

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52
Q

desirudin

A

direct thrombin inhibitor

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53
Q

drug interactions with dabigatran?

A

when pt has impaired renal fxn avoid:

  • dronedarone
  • ketoconazole
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54
Q

Drug interactions with warfarin that increase risk of bleeding?

A 
Amiodarone 
cimetidine
erythromycin
fluconazole
gemfibrozil
isoniazide
metronidazole
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55
Q

Drug interactions with warfarin that increase risk of clotting?

A

Cholestyramine

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56
Q

Idarucizumab

A

reverses affects of dabigatran

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57
Q

Drug interactions of rivaroxaban?

A 
ketoconazole
itraconazole
carbamazepine
phenytoin
rifampin
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58
Q

Drug interactions of apixaban?

A

ketoconazole
itraconazole
ritonavir
clarithromycin

Absolute contraindicated:
rifampin
carbamazepine
phenytoin
phenobarbital
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59
Q

Drug interactions with clopidogrel?

A

drugs than inhibit CYP2c19

proton pump inhibitors (omeprazole & esomeprazole)

60
Q

streptokinase

A

fibrinolytic

61
Q

urokinase

A

fibrinolytic

62
Q

alteplase

A

fibrinolytic

63
Q

reteplase

A

fibrinolytic

64
Q

tenecteplase

A

fibrinolytic

65
Q

aminocapronic acid

A

stops bleeding caused by fibrinolytics

66
Q

amyl nitrate

A

nitrate

67
Q

isosorbide dinitrate

A

nitrate

68
Q

isosorbide mononitrate

A

nitrate

69
Q

nitroglycerin

A

nitrate

70
Q

amlodipine

A

CCB

71
Q

nifedipine

A

CCB

72
Q

felodipine

A

CCB

73
Q

nicardipine

A

CCB

74
Q

bepridil

A

CCB

75
Q

diltiazem

A

CCB

76
Q

verapamil

A

CCB

77
Q

atenolol

A

BBlocker

78
Q

metoprolol

A

BBlocker

79
Q

nadolol

A

BBlocker

80
Q

propranolol

A

BBlocker

81
Q

Ranolazine

A

metabolic modifier

82
Q

class I antiarrhythmics?

A

sodium channel blockers (reduce abnormal automaticity & slow conduction)

83
Q

class II antiarrhythmics?

A

beta blockers (block sympathetic autonomic activation)

84
Q

class III antiarrhythmics?

A

potassium channel blockers (prolong refractory period/AP)

85
Q

class IV antiarrhythmics?

A

calcium channel blockers (reduce abnormal conduction & slow conduction)

86
Q

Class IA

A

PROLONG action potential and interact with sodium channel a medium length of time

87
Q

Class IB

A

SHORTEN action potential and interact with channel rapidly

88
Q

Class IC

A

least effect on sodium channel and dissociate from sodium channel slowly

89
Q

Disopyramide

A

class IA Sodium Channel-Blocking Drugs

90
Q

quinidine

A

class IA Sodium Channel-Blocking Drugs

91
Q

procainamide

A

Class IA Sodium Channel-Blocking Drugs

92
Q

lidocaine

A

Class IB Sodium Channel-Blocking Drugs

93
Q

mexiletine

A

class IB Sodium Channel-Blocking Drugs

94
Q

flecainide

A

class IC Sodium Channel-Blocking Drugs

95
Q

propafenone

A

class IC Sodium Channel-Blocking Drugs

96
Q

metoprolol

A

Class 2 antiarrhythmics

beta blocker

97
Q

esmolol

A

Class 2 antiarrhythmics

beta blocker

98
Q

atenolol

A

Class 2 antiarrhythmics

beta blocker

99
Q

amiodarone

A 
class 3
k channel blocker
prolongs AP 
Class IB, II, & IV properties
100
Q

dronedarone

A 
class 3
k channel blocker
prolongs AP 
Class IB, II, IV properties
101
Q

sotalol

A 
class 3
k channel blocker
prolongs AP 
50% beta blocking properties
102
Q

dofetilide

A 
class 3
k channel blocker
prolongs AP
103
Q

ibutilide

A 
class 3
k channel blocker
prolongs AP
104
Q

diltiazem

A

class 4 CCB

105
Q

verapamil

A

class 4 CCB

106
Q

adenosine

A

activates K+ and inhibits influx of calcium in SA node, atrium and AV node.

107
Q

magnesium

A

Uses:
To treat digitalis induced ventricular arrhythmias
To suppress drug-induced torsades de pointes
To treat supraventricular arrhythmias associated with magnesium deficiency

108
Q

potassium

A

Increasing potassium in the blood depresses ectopic pacemakers (tissue other than the conduction system depolarizing) and slows conduction

109
Q

epinephrine

A

non-selective B1&2

110
Q

ephedrine

A

non-selective B1&2

111
Q

isoproterenol

A

non-selective B1&2

112
Q

albuterol

A

short acting B2 selective

113
Q

levalbuterol

A

short acting B2 selective

114
Q

terbutaline

A

short acting B2 selective

115
Q

metaproterenol

A

short acting B2 selective

116
Q

pirbuterol

A

short acting B2 selective

117
Q

fenoterol

A

short acting B2 selective

118
Q

salmeterol

A

Long acting B2 selective

119
Q

formoterol

A

long acting B2 selective

120
Q

theophylline (PO)

A

methylxanthines

121
Q

aminophylline (IV)

A

methylxanthines

122
Q

ipratropium

A

antimuscarinic

123
Q

tiotropium

A

antimuscarinic

124
Q

aclininium

A

antimuscarinic

125
Q

umeclidinum

A

antimuscarinic

126
Q

methylprednisolone

A

systemic corticosteroid
oral
depomedrol (IM)
solumedrol (IV)

127
Q

prednisolone

A

systemic corticosteroid

128
Q

prednisone

A

systemic corticosteroid

129
Q

beclomethasone

A

ICS

130
Q

budesonide

A

ICS

131
Q

Ciclesonide

A

ICS

132
Q

Flunisolide

A

ICS

133
Q

Fluticasone

A

ICS

134
Q

Mometasone

A

ICS

135
Q

Triamcinolone

A

ICS

136
Q

Fluticasone/salmeterol

A

ICS/LABA combo

137
Q

fluticasone/vilanterol

A

ICS/LABA combo

138
Q

budesonide/formoterol

A

ICS/LABA combo

139
Q

mometasone/formoterol

A

ICS/LABA combo

140
Q

cromolyn sodium

A

cromolyn

141
Q

nedocromil

A

cromolyn

142
Q

montelukast

A

leukotriene modifier

143
Q

zafirlukast

A

leukotriene modifier

144
Q

zileuton

A

leukotriene modifier

145
Q

omalizumab

A

Anti-IgE monoclonal Antibodies

146
Q

Romflumilast

A

phosphodiesterase inhibitor

147
Q

combivant

A

albuterol & ipratoprium used in COPD

Pharm 5 (8 decks)

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