Last exam drugs Flashcards
1
Q
Digoxin: drug group
A
Digitalis Glycoside
Positive Inotrope
2
Q
Milrinone: drug group
A
Phosphodiesterase Inhibitor
Positive Inotrope
3
Q
Dobutamine: drug group
A
Positive Inotrope
Adrenoceptor Agonist
4
Q
ACEI: drug group
A
Angiotensin inhibitor
Vasodilator
5
Q
ARB: drug group
A
Angiotensin Inhibitor
Vasodilator
6
Q
Hydralazine: drug group
A
Vasodilator
7
Q
Isosorbide Dinitrate: drug group
A
Vasodilator
8
Q
Spironolactone: drug group
A
Aldosterone Antagonist
9
Q
Eplerenone: drug group
A
Aldosterone Antagonist
10
Q
Carvedilol: drug group
A
Beta adrenoreceptor blocker
11
Q
Bisoprolol: drug group
A
Beta adrenoreceptor blocker
12
Q
Metoprolol: drug group
A
Beta adrenoreceptor blocker
13
Q
Furosemide: drug group
A
Loop diuretic
14
Q
Bumetanide: drug group
A
loop diuretic
15
Q
Torsemide: drug group
A
loop Diuretic
16
Q
Ivabradine: drug group
A
Hyper polarization active cyclic nucleotide-gated channel blocker
17
Q
Sacubitril/Valsartan (Entresto): drug group
A
Angiotensin receptor Neprilysin Inhibitor
18
Q
Captopril: drug group
A
ACEI
19
Q
Enalapril: drug group
A
ACEI
20
Q
Fosinopril: drug group
A
ACEI
21
Q
lisinopril: drug group
A
ACEI
22
Q
quinapril: drug group
A
ACEI
23
Q
ramipril: drug group
A
ACEI
24
Q
tradolopril: drug group
A
ACEI
25
candesartan: drug group
ARB
26
losartan: drug group
ARB
27
valsartan: drug group
ARB
28
warfarin
vit K antagonist
29
heparin
indirect thrombin inhibitor
| unfractionated heparin
30
Enoxaparin
indirect thrombin inhibitor
| LMWH
31
dalteparin
indirect thrombin inhibitor
| LMWH
32
tinzaparin
indirect thrombin inhibitor
| LMWH
33
danaparoid
indirect thrombin inhibitor
| LMWH
34
Fondaparinux
Factor X inhibitor
35
lepirudin
direct thrombin inhibitor
36
bivalirudin
direct thrombin inhibitor
37
dabigatran
direct thrombin inhibitor
38
rivaroxaban
active factor x inhibitor
39
apixaban
active factor x inhibitor
40
ASA (asprin)
antiplatelet drugs
41
clopidigrel (plavix)
antiplatelet drug
42
dipyridamole
antiplatelet drug
43
prasugrel
antiplatelet drug
44
ticlopidine
antiplatlet drug
45
abciximab
glycoprotein IIb/IIIa receptor antagonist
46
eptifibatide
glycoprotein IIb/IIIa receptor antagonist
47
tirofiban
glycoprotein IIb/IIIa receptor antagonist
48
protamine sulfate
reverses unfractionated heparin, LMWH (not as well)
49
vit K
reverses warfarin
50
fresh frozen plasma
reverses warfarin
51
argatroban
direct thrombin inhibitor
52
desirudin
direct thrombin inhibitor
53
drug interactions with dabigatran?
when pt has impaired renal fxn avoid:
- dronedarone
- ketoconazole
54
Drug interactions with warfarin that increase risk of bleeding?
```
Amiodarone
cimetidine
erythromycin
fluconazole
gemfibrozil
isoniazide
metronidazole
```
55
Drug interactions with warfarin that increase risk of clotting?
Cholestyramine
56
Idarucizumab
reverses affects of dabigatran
57
Drug interactions of rivaroxaban?
```
ketoconazole
itraconazole
carbamazepine
phenytoin
rifampin
```
58
Drug interactions of apixaban?
ketoconazole
itraconazole
ritonavir
clarithromycin
```
Absolute contraindicated:
rifampin
carbamazepine
phenytoin
phenobarbital
```
59
Drug interactions with clopidogrel?
drugs than inhibit CYP2c19
proton pump inhibitors (omeprazole & esomeprazole)
60
streptokinase
fibrinolytic
61
urokinase
fibrinolytic
62
alteplase
fibrinolytic
63
reteplase
fibrinolytic
64
tenecteplase
fibrinolytic
65
aminocapronic acid
stops bleeding caused by fibrinolytics
66
amyl nitrate
nitrate
67
isosorbide dinitrate
nitrate
68
isosorbide mononitrate
nitrate
69
nitroglycerin
nitrate
70
amlodipine
CCB
71
nifedipine
CCB
72
felodipine
CCB
73
nicardipine
CCB
74
bepridil
CCB
75
diltiazem
CCB
76
verapamil
CCB
77
atenolol
BBlocker
78
metoprolol
BBlocker
79
nadolol
BBlocker
80
propranolol
BBlocker
81
Ranolazine
metabolic modifier
82
class I antiarrhythmics?
sodium channel blockers (reduce abnormal automaticity & slow conduction)
83
class II antiarrhythmics?
beta blockers (block sympathetic autonomic activation)
84
class III antiarrhythmics?
potassium channel blockers (prolong refractory period/AP)
85
class IV antiarrhythmics?
calcium channel blockers (reduce abnormal conduction & slow conduction)
86
Class IA
PROLONG action potential and interact with sodium channel a medium length of time
87
Class IB
SHORTEN action potential and interact with channel rapidly
88
Class IC
least effect on sodium channel and dissociate from sodium channel slowly
89
Disopyramide
class IA Sodium Channel-Blocking Drugs
90
quinidine
class IA Sodium Channel-Blocking Drugs
91
procainamide
Class IA Sodium Channel-Blocking Drugs
92
lidocaine
Class IB Sodium Channel-Blocking Drugs
93
mexiletine
class IB Sodium Channel-Blocking Drugs
94
flecainide
class IC Sodium Channel-Blocking Drugs
95
propafenone
class IC Sodium Channel-Blocking Drugs
96
metoprolol
Class 2 antiarrhythmics
| beta blocker
97
esmolol
Class 2 antiarrhythmics
| beta blocker
98
atenolol
Class 2 antiarrhythmics
| beta blocker
99
amiodarone
```
class 3
k channel blocker
prolongs AP
Class IB, II, & IV properties
```
100
dronedarone
```
class 3
k channel blocker
prolongs AP
Class IB, II, IV properties
```
101
sotalol
```
class 3
k channel blocker
prolongs AP
50% beta blocking properties
```
102
dofetilide
```
class 3
k channel blocker
prolongs AP
```
103
ibutilide
```
class 3
k channel blocker
prolongs AP
```
104
diltiazem
class 4 CCB
105
verapamil
class 4 CCB
106
adenosine
activates K+ and inhibits influx of calcium in SA node, atrium and AV node.
107
magnesium
Uses:
To treat digitalis induced ventricular arrhythmias
To suppress drug-induced torsades de pointes
To treat supraventricular arrhythmias associated with magnesium deficiency
108
potassium
Increasing potassium in the blood depresses ectopic pacemakers (tissue other than the conduction system depolarizing) and slows conduction
109
epinephrine
non-selective B1&2
110
ephedrine
non-selective B1&2
111
isoproterenol
non-selective B1&2
112
albuterol
short acting B2 selective
113
levalbuterol
short acting B2 selective
114
terbutaline
short acting B2 selective
115
metaproterenol
short acting B2 selective
116
pirbuterol
short acting B2 selective
117
fenoterol
short acting B2 selective
118
salmeterol
Long acting B2 selective
119
formoterol
long acting B2 selective
120
theophylline (PO)
methylxanthines
121
aminophylline (IV)
methylxanthines
122
ipratropium
antimuscarinic
123
tiotropium
antimuscarinic
124
aclininium
antimuscarinic
125
umeclidinum
antimuscarinic
126
methylprednisolone
systemic corticosteroid
oral
depomedrol (IM)
solumedrol (IV)
127
prednisolone
systemic corticosteroid
128
prednisone
systemic corticosteroid
129
beclomethasone
ICS
130
budesonide
ICS
131
Ciclesonide
ICS
132
Flunisolide
ICS
133
Fluticasone
ICS
134
Mometasone
ICS
135
Triamcinolone
ICS
136
Fluticasone/salmeterol
ICS/LABA combo
137
fluticasone/vilanterol
ICS/LABA combo
138
budesonide/formoterol
ICS/LABA combo
139
mometasone/formoterol
ICS/LABA combo
140
cromolyn sodium
cromolyn
141
nedocromil
cromolyn
142
montelukast
leukotriene modifier
143
zafirlukast
leukotriene modifier
144
zileuton
leukotriene modifier
145
omalizumab
Anti-IgE monoclonal Antibodies
146
Romflumilast
phosphodiesterase inhibitor
147
combivant
albuterol & ipratoprium used in COPD
