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Pharm 5 > Drugs for HTN > Flashcards

Drugs for HTN Flashcards

1
Q

Chlorthalidone

A

Thiazide Diuretic

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2
Q

hydrochlorothiazide

A

thiazide diuretic

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3
Q

metolazone

A

thiazide diuretic

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4
Q

indapamide

A

thiazide diuretic

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5
Q

chlorthiazide

A

thiazide diuretic

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6
Q

methyldopa

A

centrally acting sympathoplegic

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7
Q

clonidine

A

centrally acting sympathoplegic

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8
Q

Propranolol

A

non-selective beta blocker

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9
Q

Nadolol

A

non-selective beta blocker

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10
Q

Carteolol

A

non-selective beta blocker

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11
Q

metoprolol

A

selective beta blocker

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12
Q

atenolol

A

selective beta blocker

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13
Q

betaxolol

A

selective beta blocker

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14
Q

esmolol

A

selective beta blocker

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15
Q

bisoprolol

A

selective beta blocker

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16
Q

nebivolol

A

selective beta blocker

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17
Q

pindolol

A

partial agonist beta blocker

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18
Q

acebutolol

A

partial agonist beta blocker

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19
Q

penbutolol

A

partial agonist beta blocker

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20
Q

labetalol

A

beta and alpha antagonist

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21
Q

carvedilol

A

beta and alpha antagonist

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22
Q

prazosin

A

alpha antagonist

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23
Q

doxazosin

A

alpha antagonist

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24
Q

terazosin

A

alpha antagonist

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25
Q

hydralazine

A

vasodilator

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26
Q

minoxidil

A

vasodilator

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27
Q

sodium nitroprusside

A

IV vasodilator

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28
Q

diazoxide

A

IV vasodilator

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29
Q

fenolopam

A

IV vasodilator

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30
Q

nitroglycerin

A

IV vasodilator

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31
Q

verapamil

A

nondihydropyridine ca channel blocker

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32
Q

diltazine

A

nondihydropyridine ca channel blocker

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33
Q

amlopdipine

A

dihydropyridine ca channel blocker

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34
Q

nifedipine

A

dihydropyridine ca channel blocker

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35
Q

felodipine

A

dihydropyridine ca channel blocker

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36
Q

isradipine

A

dihydropyridine ca channel blocker

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37
Q

nicardipine

A

dihydropyridine ca channel blocker

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38
Q

nislodipine

A

dihydropyridine ca channel blocker

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39
Q

benazepril

A

ACEI

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40
Q

Captopril

A

ACEI

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41
Q

Fosinopril

A

ACEI

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42
Q

Enalapril

A

ACEI

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43
Q

Lisinopril

A

ACEI

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44
Q

Moexipril

A

ACEI

45
Q

Quinapril

A

ACEI

46
Q

Ramipril

A

ACEI

47
Q

Trandolapril

A

ACEI

48
Q

Candesartan

A

ARB

49
Q

Eprosartan

A

ARB

50
Q

Irbesartan

A

ARB

51
Q

Losartan

A

ARB

52
Q

Olmesartan

A

ARB

53
Q

Telmisartan

A

ARB

54
Q

Valsartan

A

ARB

55
Q

post MI anti-HTN?

A

beta blockers
ACEI
ALD antagonists

56
Q

Kidney disease

A

ACEI
ARB

Beta blocker
diuretic
CCB

57
Q

Over 65

A

diuretic
ACEI
CCB

avoid: centrally acting A2 agonist

58
Q

African Americans

A

diuretic
ACEI
ARB
CCB

avoid: beta blockers

59
Q

Pregnant

A

methyldopa
labetalol

avoid: ACEI, ARB

60
Q

Angina pectoris

A

beta blocker
CCB

avoid: hydralazine, mindoxidil (vasodilators that cause tachycardia/angina)

61
Q

CHF

A

ACEI
ARB
Beta blockers (Stable)
diuretic

62
Q

stroke prevention

A

diuretic
ACEI
ARB

63
Q

asthma

A

ACEI
ARB
CCB

avoid: beta blocker

64
Q

BPH

A

alpha antagonist

65
Q

migraine

A

beta blocker

CCB

66
Q

osteoporosis

A

diuretic

67
Q

Aliskiren

A

binds activation site of renin

68
Q

ambrisentan

A

endothelin antagonist (pulmonary artery HTN)

69
Q

bosentan

A

endothelin antagonist (pulmonary artery HTN)

70
Q

acetazolamide

A

carbonic anhydrase inhibitor (glaucoma)

71
Q

ethacrynic acid

A

loop diuretic for sulfa allergy

72
Q

furosemide

A

loop diuretic

sulfonamide type

73
Q

bumetanide

A

loop diuretic

sulfonamide type

74
Q

torsemide

A

loop diuretic

sulfonamide type

75
Q

spironolactone

A

potassium sparing diuretic aldosterone receptor antagonists

76
Q

eplerenone

A

potassium sparing diuretic aldosterone receptor antagonist

77
Q

amiloride

A

potassium sparing diuretic

inhibit Na channel

78
Q

triamterene

A

potassium sparing diuretic

inhibit Na channel

79
Q

Mannitol

A

osmotic diuretic

80
Q

Rosuvastatin

A

high potency HMG-COA Reductase Inhibitors

aka crestor

81
Q

atrovastatin

A

high potency HMG-COA Reductase Inhibitors

aka lipitor

82
Q

lovastatin

A

moderate to low potency

HMG-COA Reductase Inhibitors

83
Q

fluvastatin

A

moderate to low potency HMG-COA Reductase Inhibitors

84
Q

pravastatin

A

moderate to low potency HMG-COA Reductase Inhibitors

85
Q

simvastatin

A

moderate to low potency HMG-COA Reductase Inhibitors

86
Q

pitavastatin

A

moderate to low potency HMG-COA Reductase Inhibitors

87
Q

vitamin B3

A

niacin

88
Q

nicotinic acid

A

niacin

89
Q

niaspan

A

niacin

90
Q

gemfibrozil

A

Fibric acid derivative

91
Q

fenofibrate

A

fibric acid derivative

92
Q

Lovaza

A

omega-3-acid ethyl esters

93
Q

vascepa

A

omega-3-acid ethyl esterase

94
Q

colestipol

A

bile acid binding resins

95
Q

cholestyramine

A

bile acid binding resins

96
Q

colesevelam

A

bile acid binding resins

97
Q

ezetimibe

A

cholesterol absorption inhibitor

98
Q

alirocumab

A

PCSK9 inhibitors

99
Q

evolocumab

A

PCSK9 inhibitors

100
Q

diet modification of LDL and TG?

A

LDL- decrease 10-15%

TG - decrease 10-20%

101
Q

HMG-CoA reductase inhibitors modification of LDL, TG, and HDL?

A

LDL - decrease 24-60%
TG - 7-40%
HDL - increase 5-15%

102
Q

most effective drug therapy for elevated LDL?

A

statins

103
Q

Bile acid binding resins modification of LDL, TG, and HDL?

A

LDL- decreased 15-26%
TG - decrease 0-5%
HDL- increase 3-6%

104
Q

Fibric acid derivatives modification of LDL, TG, HDL?

A

LDL - decrease 5-20%
TG- decrease 30-55%
HDL - increase 18-22%

105
Q

most powerful drug therapy for decreasing TG?

A

fibric acid derivatives

106
Q

ezetimibe modifications of LDL, HDL, TG?

A

LDL- decrease 18-20%
TG decrease 5-10%
HDL- increase 1-5%

107
Q

niacin modifications of LDL, HDL, and TG?

A

LDL - decrease 15-26%
TG - decrease 20-50%
HDL: increase 15-26%

108
Q

best drug therapy for increasing HDL?

A

niacin

Pharm 5 (8 decks)

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