Language Systems And Aphasias Flashcards

1
Q

What are the 2 principle structures of the neurocircuitry of language function

A

Broca’s Area

Wernicke’s Area

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2
Q

What connects Broca’s area and Wernicke’s area?

A

Accurate fasciculus and other peri-Sylvia connections

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3
Q

What happens if you disrupt the arcuate fasciculus

A

Both areas work, but problems connecting the 2 areas

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4
Q

Conscious auditory processing in primary auditory cortex

A

Lateral lemniscus to the MGN (medial = music)
Then to the
primary auditory cortex: superior temporal gyrus, within lateral fissure

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5
Q

Where is Heschl’s Gyrus

A

On the inside portion of the temporal lobe near the insula

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6
Q

Where is the temporal plane

A

On the temporal lobe, kind of a shelf when you pull it back

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7
Q

How are the language areas in each hemisphere connected

A

Via the corpus callosum

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8
Q

Hemispheric lateralization of language function

A

One “dominant side” processes the semantic aspects of language, while the “non-dominant” side processes non-verbal aspects of language: tone of voice, emotion, cadence, rhythm, accent

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9
Q

What does the dominant side processes

A

Semantic aspects of language

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10
Q

That does the non dominant side processes

A

Non verbal aspects of language: tone of voice, emotion, cadence, rhythm, accent

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11
Q

What side of the brain dominant are most people

A

Left

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12
Q

Non-verbal aspects: tone of voice, emotion, emphasis, cadence, rhythm, accent

A

Prosody

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13
Q

In people who are left dominant, what does the left side of the brain processes

A

Semantic aspects of language: meaning

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14
Q

In left dominant individuals, what does the right side of the brain process

A

Prosody

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15
Q

Sequence of regions and projections for language circuitry for reading aloud or naming objects

A
  1. Primary visual cortex
  2. Higher order visual cortical areas
  3. Parietal-temporal-occipital association cortex (angular gyrus)
  4. Wernicke’s area
  5. Broca’s area
  6. Motor region of the face
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16
Q

Fluent speech

A
  • effortless, good articulation, grammatical
  • prosody is intact: not a monotone or emotionally flat quality
  • grammatical-caution: looking for change from patients own normal pattern
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17
Q

Non fluent

A
  • laborious, inarticulate
  • degradation in sentence structure: missing words, adjectives, adverbs
  • in severe cases, reduced to telegraphic speech- nouns and verses only
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18
Q

How do you communicate with someone who does not have fluent speech

A

Switch from patient naming stimuli to asking yes-no questions

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19
Q

Volume of speech

A

Amount, not volume
Quantity/speed produced

Full sentences: high volume
Few words: low volume

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20
Q

Impaired/absent comprehension, but “fluent” and “high volume” of speech

A

Wernicke’s Aphasia

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21
Q

Coherency of the speech in Wernicke’s aphasia

A

May or may not be coherent, but will not understand questioning during exam

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22
Q

What’s another way of describing how the patient forms sentences in Wernicke’s aphasia

A

Word-Salad

-non-sense sentences with real words, real syllables, or non-words

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23
Q

Patients awareness of having Wernicke’s Aphasie

A

Typically unaware if deficit; frustrates by interactions until diagnosed

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24
Q

Intact comprehension, but impaired speech production

A

Broca’s Aphasia

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25
Q

Low fluency/volume of speech

A

Broca’s Aphasia

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26
Q

Patient awareness of having Broca’s aphasia

A

Patients may be aware of deficit (and distressed by it), especially before being examined and diagnosed

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27
Q

Damage to Broca’s also does what

A

Severs projections to ipsilateral (left) premotor cortex

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28
Q

What does the damage to the projections to ipsilateral premotor cortex in Broca’s area damage do

A

Makes it so patient cannot write with contralteral hand (right)
Spoken/written impairment

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29
Q

What do left sided infarcts do to the premotor cortex

A

Prevents activation of right premotor cortex (non injured side) thus writing apraxia for left hand

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30
Q

When the patient has a deficit in Broca’s area and the premotor cortex is damaged, what can the patient do to answer questions since they cannot write

A

They can still point to correctly answer questions (non language motor response, does NOT require Broca’s area)

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31
Q

Instant comprehension and intact speech production when tested separately, but deficit lies in coordinating comprehension and spoken responses

A

Conduction aphasia due to arcus the fasciculus damage.

32
Q

How do you confirm comprehension in conduction aphasia due to accurate fasciculus damage

A

By patient nodding head to answer questions (comprehension and non verbal response)

33
Q

How can speech production be confirmed in patients with conduction aphasia due to accurate fasciculus damage

A

By examiner pointing to elicit spoken answers rather than asking spoken questions. Patient can correctly name family members if examiner points to them

34
Q

What is conduction aphasia due to arcuate fasciculus damage called

A

Disconnection syndrome

35
Q

What would an infarct to MCA superior territory cause

A

Broca’s or conduction aphasia

36
Q

What would infarct to MCA inferior territory cause

A

Wrenickes or conduction aphasia

37
Q

What would MCA superior and inferior infarct cause (proximal to bifurcation)

A

Global aphasia, combination of Brocas and wernickes

38
Q

MCA-ACA watershed infarct

A

-motor transcortical aphasia (mild version of Broca’s)
-isolates an intact Broca’s area from other motor areas
Non fluent or low fluency like Broca’s except the patient can repeat words or doe so spontaneously/repetitively
-other motor defects, especially proximal arm/leg

39
Q

What’s the difference between regular Broca’s aphasia and the type of aphasia you see with an MCA-ACA watershed infarct

A

It’s low fluency like broca’s, but the patient can repeat words or does so spontaneously/repetitively

40
Q

MCA-PCA watershed infarct

A
  • Sensory transcortical aphasia
  • isolates an intact Wernicke’s area from visual areas, fluent aphasia like in Wernicke’s bu patient can repeat words or does so spontaneously/repetitively
41
Q

What’s the main differnce between the symptoms of an MCA-ACA watershed infarct and an MCA-PCA watershed infarct

A

MCA ACA: like Brocas but can repeat words

MCA-PCA: like Wernicke’s but can repeat words

42
Q

What is the common theme with the symptoms associated with MCA-ACA and MCA-PCA watershed infarcts

A

They both have different types of aphasias but in both types of infarct, they can repeat words

43
Q

What kind of infarct results in a motor transcortical aphasia

A

MCA-ACA watershed infarct

44
Q

What kind of infarct results in a sensory transcortical aphasia

A

MCA-PCA watershed infarct

45
Q

Classification tree for apshasia and infarcts

A
  1. Is patient fluent?
  2. Comprehends language?
  3. Can repeat single words?
46
Q

What are the most common types of aphasias

A
  • broca’s aphasia
  • Transcortical motor aphasia
  • Wernicke’s aphasia
  • transcortical sensory aphasia
47
Q

Inability to name stimuli presented

A

Anomic

48
Q

What’s the difference between Broca’s aphasia and transcortical motor aphasia?

A

Transcortical motor aphasia the patient repeats words, in brocas they don’t repeat

49
Q

What is the difference between Wernicke’s aphasia and transcortical sensory aphasia

A

Transcortical sensory aphasia the patient repeats words, in Wernickes they do not

50
Q

Wernicke’s and Broca’s areas are intact, but are disconnected from each other. Can comprehend and language output is fluent, but cannot produce desired verbal response to a question.

A

Conduction aphasia

51
Q

An infarct along the MCA-PCA watershed or isolated MCA branch occlusion in the parieto-occipital-temporal junction would cause what kind of aphasia

A

Conduction aphasia

52
Q

Fluency in Brocas

A

Nonfuent

53
Q

Fluency in Wernickes

A

Fluent

54
Q

Fluency in conduction aphasia

A

Fluent

55
Q

Fluency in global aphasia

A

Nonfleunt

56
Q

Expression in Brock’s

A

Impaired

57
Q

Expression in Wernickes

A

Unintelligible

58
Q

Expression in conduction aphasia

A

Some paraphrasing (some unintelligible)

59
Q

Expression in global aphasia

A

Impaired

60
Q

Comprehension in Broca’s

A

Relatively preserved

61
Q

Comprehension in Wernicke’s

A

Impaired

62
Q

Comprehension in conduction aphasia

A

Preserved

63
Q

Comprehension in global aphasia

A

Impaired

64
Q

Naming in broca’s

A

Impaired

65
Q

Naming in Wernickes

A

Impaired

66
Q

Naming in conduction aphasia

A

May be impaired

67
Q

Naming in global aphasia

A

Impaired

68
Q

Lesion site for Broca;s aphasia

A

Left frontal operculum

69
Q

Lesion site for Wernickes

A

Left superior temporal and inferior parietal corticospinal

70
Q

Lesion site for conduction aphasia

A

Left accurate fasciculus

71
Q

Lesion site for global aphasaia

A

Whole perisylvian region

72
Q

Loss of ability to read words, typically after PCA infarct

A

alexia

73
Q

When do you typically get alexia

A

After PCA infarct

74
Q

Alexia without agraphia

A

Alexia without the loss of ability to write (including written responses to the examiner )

75
Q

Circuitry affected in alexia without agraphia

A

Infarct in left primary visual cortex not only induces right homonymous hemianopsia, but also blocks projections from intact right visual cortex from crossing midline and reaching the left angular gyrus

76
Q

Alexia without agraphia and reading

A

Loss of reading using wither eye. Also cant see left half of space