Labour and Delivery Flashcards
Define parturition
Transition from being preg to non-preg state
Define labour
Physiological process by which fetus is expelled from uterus to outside world
Define delivery
Method of expulsion of fetus, transforming fetus to neonate
What are the stages of labour?
First stage = creation of birth canal
Second stage = descent, rotation, delivery
Third stage = placental delivery
Outline the first stage of labour
Contractions begin
Descent of fetal head into birth canal
Creation of birth canal
1) latent phase = slow cervical softening, shortening, opening
2) active phase = faster rate of change, regular contractions
Outline the second stage of labour
Fetal head descent and rotation through the dilated cervix, birth canal and delivery
1) passive phase = descent and rotation
2) active phase = maternal effort to expel the fetus and achieve birth
Outline the third stage of labour
Delivery of placenta
Usually 5-15 mins
How does labour get initiated?
Rise in oestrogen:progesterone ratio
Prostaglandins = initiate softening of cervix, maintain/initiate uterine contractions
Oxytocin = uterine contractions
Outline the functions of prostaglandins
Induce cervical ripening
Induce cervical contractions
Increase myometrial sensitivity to oxytocin
Raise intracellular Ca = myometrial cell contract
Enhance myometrial gap junctions = strengthen contractions
What is cervical ripening?
The changes in the cervix when labour is being initiated
1) reduction in collagen
2) increases in GAGs
3) increase in hyaluronic acid
4) reduced aggregation of collagen fibres
Due to oestrogen, relaxin and prostaglandins breaking down the connective tissue
Where are prostaglandins produced?
Mainly in myometrium and decidua
Increased synthesis by amnion in third trimester
Released from cervical stretching
How does progesterone effect contractions?
Inhibits
Relative fall in progesterone = facilitates myometral excitability
Where is oxytocin secreted from and how is it controlled?
Secreted by posterior pituitary
Controlled by hypothalamus = +ve feedback from cervix and vagina (Ferguson reflex)
What is the role of oxytocin?
Initiates uterine contractions
Increases prod of prostaglandins which increase the contractions further
What increases the number of oxytocin receptors?
Oestrogen