Lab Values Flashcards
normal range for potassium
K+ 3.5-5
normal functions for potassium
maintain resting potential of skeletal, smooth, and cardiac muscle - muscle function and nerve impulse conduction
what can cause hypokalemia?
(less than 3.5)
- diarrhea
- diabetic ketoacidosis
- potassium wasting diuretics
signs and symptoms of hypokalemia
(less than 3.5)
- muscle weakness - life-threatening if respiratory muscles
- cardiac dysrhythmias
what can hyperkalemia?
(greater than 5)
- oliguria
- kidney dysfunction
signs and symptoms of hyperkalemia?
(greater than 5)
- muscle weakness
- ascending paralysis
- cardiac dysrhythmias
what is the main concern with hyperkalemia and hypokalemia? K+
arrhythmias and dysrhythmias
what is the normal range for calcium?
Ca+ 8.4-10.5
what is the normal function of calcium?
influences excitability of nerve and muscle cells - muscle contraction
where is calcium found?
blood, teeth, and blood clotting
what can cause hypocalcemia?
(less than 8.4)
- diarrhea
- malabsorption syndrome like chron’s disease
- vitamin D deficiency
- hypoparathyroidism
what vitamin is needed to absorb calcium?
vitamin D
signs and symptoms of hypocalcemia?
(less than 8.4)
- numbness
- tingling
- positive chvostek’s sign
- positive trousseau sign
chvostek’s sign
facial muscle spams caused by tapping a spot close to the ear
trousseau’s sign
hand spasm due to pressure on the arm like a blood pressure cough
paget’s disease
interferes with bone replacement cycle
what can cause hypercalcemia?
(greater than 10.5)
- hyperparathyroidism
- paget’s disease
- thiazide diuretics
signs and symptoms of hypercalcemia
(greater than 10.5)
- decreased reflexes
- bone pain
- weakness
- confusion
- lethargy
- decreased level of consciousness
the normal level of magnesium?
Mg2+ 1.5-2.5
what can cause hypomagnesemia?
(less than 1.5)
- dietary restrictions
- diuretics
- malabsorption
- diabetic ketoacidosis
signs and symptoms of hypomagnesemia?
(less than 1.5)
- hypocalcemia
- irritable
- hypertension
- involuntary movements
- hyperactive deep tendons reflex
- positive chvostek’s sign
- positive trousseau’s sign
what can cause hypermagnesemia?
(greater than 2.5)
- end-stage renal disease
- preeclampsia
- administration of IV mag2+
signs and symptoms of hypermagnesemia?
(greater than 2.5)
- lethargy
- absent or diminished deep tendon reflex
- EKG changes
- nausea and vomiting
- impaired breathing
- cardiac arrest
- hypotension
relationship between magnesium, calcium, and phosphate
magnesium and calcium are inversely related to phosphate
- if magnesium and calcium are high, then phosphate will be low
- of magnesium and calcium are low, the phosphate will be high
normal hematocrit range
men - 45-52%
women - 37-48%
what is hematocrit?
percent of the blood that is RBC
what increases hematocrit range?
increases with dehydration
normal hemaglobin range?
men - 13-18
women - 12-16
what can cause low hemoglobin levels?
(below 13 in men and 12 in women)
- blood loss
- hemolytic anemia
- bone marrow suppression
symptoms of low hemoglobin?
(below 13 in men and 12 in women)
- dyspnea
what is hemoglobin?
part of the RBC that carries oxygen
what substance is needed to make hemoglobin?
iron
under what value of hemoglobin do you become concerned for a blood transfusion?
HGB under 10
normal relationship between hematocrit and hemoglobin?
hematocrit should be 3 times higher than hemoglobin
what is the normal range for RBC?
men 4.7 - 6.1
women 4.2-5.4
what is secreted by the kidneys to stimulate RBC production in the bone marrow?
erythropoietin
what is inside a RBC?
hemaglobin - carries O2
where are RBC made?
bone marrow
what is required to make RBC?
B12 and folic acid
what is anemia?
low RBC - decreased erythrocytes
what are signs and symptoms of anemia?
pale, weak, SOB with activity
what is polycythemia?
high RBC
what does polycythemia due to blood?
blood becomes more viscous (thick)
what does polycythemia decrease?
decreases percent of cellular O2
what is the normal range for WBC?
5000-1000
what does WBC do?
fight infection
where are WBC made?
bone marrow and lymphoid tissue
what are the two types of WBC?
granulocytes and agrunolocytes
leukopenia
(less than 5,000)
- low levels of WBC - risk for infection
leukemia
abnormal WBC - risk for infection
leukocytosis
(greater than 10,000)
- high levels of WBC - fighting infection
normal level for creatinine?
0.8-1.4
what is creatinine?
waste product excreted by kidneys
what do creatinine levels evaluate?
kidney function (some antibiotics are nephrotoxic)
normal level for blood urea nitrogen (BUN)?
10-20
what do BUN levels evaluate?
kidney function
signs and symptoms of high BUN levels?
(greater than 20)
- result of dehydration
- may indicate low kidney function
- mental confusion
two kinds of total protein?
albumin and globulin
what regulates albumin and globulins (total protein)?
regulated by the liver and kidneys
what is the function of albumin?
- carrying drugs
- fluid balance
- maintaining osmotic pressure
what is the function of globulins?
immunity
what does pre albumin evaluate?
nutritional status
normal bilirubin level?
0.2-1.0
what is bilirubin?
from destructed RBCs in the liver
what does bile do?
give color to stool
what do high bilirubin levels cause?
(greater than 1.0)
jaundice
what should cholesterol be less than total?
150
what does high cholesterol lead to?
(greater than 150)
- leads to atherosclerosis which can decrease blood flow and cause a MI or TIA
what is ldl in terms of cholesterol?
l = lethal, bad cholesterol
what is hdl in terms of cholesterol?
h = healthy, good cholesterol
what do enzymes always end in?
“-ase”
what is an isoenzyme?
can isolate the source of tissue damage
- damaged tissue will release the enzyme
BNP
another marker for CHF
elevated cardiac tropin
elevation shows cardiac event
the normal range for platelet count/thrombocyte count
150,000-400,000
thrombocytopenia
(less than 150,000)
- idiopathic
- bone marrow disease
- drugs and radiation therapy
thrombocytosis
(greater than 400,000)
- malignant tumors
- splenectomy
aspirin and platelets
asprin interferes with clotting mechanism and the body compensates by producing platelets
normal level for sodium
135-145
what is hyponatremia?
(less than 135)
- gain of more water than salt
- loss of more salt than water
- cells swell
signs and symptoms of hyponatremia?
(less than 135)
- decreased level of consciousness
- confusion
- lethargy
- coma
- seizures if it occurs rapidly
what is hypernatremia?
(greater than 145)
- loss of more water than salt
- gain of more salt than water
- cells shrivel
signs and symptoms of hypernatremia?
(greater than 145)
- decreased level of consciousness
- confusion
- lethargy
- coma
- thirst
- seizures if it occurs rapidly