Lab/Pocket Pets

Question 1

(T/F) It is mandated by law that every institution that uses animals must have an institutional animal care and use committee.

Answer 1

(T)

Question 2

How often does every place an animal is housed or brought at an institution need to be inspected by the IACUC?

Answer 2

(Every 6 months)

Question 3

Who enforces the animal welfare act?

Answer 3

(The USDA)

Question 4

What animals are covered by the public health service policy?

Answer 4

(All animals used in public health service-funded research which includes the NIH, CDC, FDA, and NSF)

Question 5

Who enforces the good laboratory practices (GLP)?

Answer 5

(The FDA)

Question 6

(T/F) The AAALAC (Association for Assessment and Accreditation of Laboratory and Animal Care) program is mandatory and involves site visits to assess animal programs every 3 years.

Answer 6

(F, it is voluntary, all else is true)

Question 7

Quarantine for laboratories using rodents is typically how long?

Answer 7

(4 weeks)

Question 8

Where is the quarantine room in the room order for feeding/cleaning and what is the air pressure inside the room relative to the hallway?

Answer 8

(Quarantine room should be dead last on your list of rooms and it should have negative pressure compared to the hallway)

Question 9

How often should laboratory rodents be tested for rodent specific bacteria, viruses, parasites, etc. as a part of a rodent health monitoring program?

Answer 9

(Quarterly)

Question 10

What type of testing is used in the environmental testing surveillance method?

Answer 10

(PCR)

Question 11

What is the rule of thumb for when to consider an outbreak of a disease in a laboratory over?

Answer 11

(Two consecutive negative screens of 100% of cages)

Question 12

What is the significance of the harderian gland?

Answer 12

(It is a gland that produces porphyrin when the animal is stressed which can look like they are bleeding from their eyes but they are not)

Question 13

Is the anogenital distance shorter in male or female rats and mice?

Answer 13

(Female)

Question 14

What is the murine parainfluenza virus type 1 which can infect other small rodents but only shows clinical signs of respiratory problems, pneumonia, and growth stunting in mice?

Answer 14

(Sendai virus)

Question 15

What is the causative agent of tyzzer’s disease?

Answer 15

(Clostridium piliforme +/- other species)

Question 16

(T/F) Tyzzer’s disease is zoonotic.

Answer 16

(T)

Question 17

What is the highly contagious coronaviral disease of rats that is associated with dry eyes, no saliva, and weight loss?

Answer 17

(Sialodacryoadenitis virus)

Question 18

(T/F) Rats who obtained an infection with sialodacryoadenitis virus cannot be reinfected once their initial infection resolves.

Answer 18

(T)

Question 19

What is the most common type of tumor that causes mammary tumors in rats and mice?

Answer 19

(Fibroadenoma)

Question 20

Which teeth are primarily affected by dental problems in rats and mice?

Answer 20

(The incisors)

Question 21

What type of day/night activity do hamsters have?

Answer 21

(Crepuscular → most active at dawn and dusk)

Question 22

(T/F) Hamsters have a cecum and are cecal fermenters.

Answer 22

(T)

Question 23

Is the anogenital distance greater for hamsters in males or females?

Answer 23

(Males)

Question 24

What is the causative agent of proliferative ileitis/enteritis aka wet tail in hamsters?

Answer 24

(Clostridium difficile +/- other species)

Question 25

What disease of hamsters occurs post-antibiotic therapy or in many stress-inducing time periods?

Answer 25

(Proliferative ileitis/enteritis)

Question 26

How can you reduce instances of pneumonia in hamsters? Two answers.

Answer 26

(Eliminate stress and reduce stocking densities)

Question 27

What is the difference between wet tail and tyzzer’s disease in hamsters?

Answer 27

(Tyzzer’s disease is more systemic, death is more acute whereas wet tail is a few days duration)

Question 28

Is the anogenital distance greater for gerbils in males or females?

Answer 28

(Males)

Question 29

What is the root cause of nasal dermatitis in gerbils?

Answer 29

(Stress → leads to irritation from porphyrin secretions and secondary bacterial infections)

Question 30

What suborder do guinea pigs belong to?

Answer 30

(Hystricomorpha)

Question 31

Do animals in the suborder hystricomorpha or myomorpha produce precocious offspring?

Answer 31

(Hystricomorpha)

Question 32

What is the normal presentation and pH of guinea pig urine?

Answer 32

(Thick and cloudy with a pH of 9)

Question 33

What vitamin do guinea pigs need supplemented daily?

Answer 33

(Vitamin C)

Question 34

Is the anogenital distance for guinea pigs larger in males or females?

Answer 34

(You don’t use anogenital distance for g pigs instead females have a Y shaped opening while the males is straight)

Question 35

Why do female guinea pigs need to be bred and deliver her first litter prior to 6-8 months of age?

Answer 35

(Bc if she does not, all subsequent litters will have to be born by C-section because the pubic symphysis will have undergone permanent fusion)

Question 36

What physiological process is impaired by a vitamin C deficiency in g pigs?

Answer 36

(Collagen synthesis → gives rise to respiratory dz, malocclusion, diarrhea, pododermatitis, lameness, enlarged long bone junctions, joint stiffness)

Question 37

What is the causative agent of antibiotic-associated enterotoxemia in g pigs that occurs when normal GI flora is disrupted and can result in anorexia, diarrhea, dehydration, hypothermia, and sudden death?

Answer 37

(Clostridium difficile)

Question 38

What is the causative agent of cervical lymphadenitis in g pigs?

Answer 38

(Streptococcus zooepidemicus)

Question 39

What is the minimum amount of fiber needed in a domestic rabbit's diet in percentage?

Answer 39

(18%)

Question 40

What is the causative agent of snuffles which is a bacterial infection of the tear ducts and nasal sinuses that can occur due to shipping, stress, respiratory irritation, and other bacterial infections?

Answer 40

(Pasteurella multocida)

Question 41

What are the possible causes of GI stasis in rabbits? Three answers.

Answer 41

(Stress, low fiber diets, and inadequate water consumption)

Question 42

(T/F) Secondary bacterial infections associated with cuterebriasis are rare.

Answer 42

(T)

Question 43

What are the clinicals signs associated with Cheyletiella parasitovorax infections in rabbits? Two answers.

Answer 43

(Moderate hair loss and scaly skin)

Question 44

(T/F) Ferrets are omnivores.

Answer 44

(F, carnivores)

Question 45

Pancreatic endocrine tumors of ferrets cause hypo/hyperinsulinism (choose one) and hypo/hyperglycemia (choose).

Answer 45

(Hyperinsulinemia and hypoglycemia)

Question 46

Adrenocortical tumors in ferrets result in what disease?

Answer 46

(Hyperadrenocorticism)

Question 47

(T/F) Ferrets can get distemper.

Answer 47

(T)