Lab 6 Flashcards
1
Q
Incoherent formulations:
- Heterogenous
- Colloidal
- Homogenous
A
- Heterogenous: Powders, emulsion, suspension, granules
- Colloidal: Colloidal solution, some stock solutions
- Homogenous: Solutions, tinctures
2
Q
Coherent formulations:
- Heterogenous
- Colloidal
A
- Heterogenous: Ointment, pastes, creams, tablets, suppositories
- Colloidal: Gels
3
Q
Emulsions
A
Liquid preparations in which the active ingredients are dispersed (emulsified) in a suitable liquid vehicle
- Emulsions: Dispersed phase is liquid
4
Q
Suspensions
A
Liquid preparations in which the active ingredients:
- Are dispersed in a suitable liquid vehicle
- In case of suspensions, the dispersed phase is solid
5
Q
Ointment
A
A single-phase base in which solids or liquids may be dispersed
6
Q
Cream
A
Multiphase preparations consisting of a lipophilic phase and an aqueous phase
7
Q
Common pH-sensitive polymers used in drug delivery
A
- Aminoalkyl methacrylate copolymer
- Hydroxypropyl-methylcellulose phthalate
8
Q
Ingredients of the capsule
A
- Resin - Shell
- Polymer - Alginate
- Plasticiser
- Preservative
- Lubricant
- Sweetener
- Opacifer
9
Q
Give the antiulcer drugs
A
- Antacids
- Inhibition of acid secretion
- H2-antagonists
- Proton pump inhibitors
- Enhancer of the mucous membrane
- PGE-analogs
- Sucralfate
- Bismuth salts
10
Q
Proton pump inhibitors (PPI)
A
Omeprazole, Pantoprazole
- Pharmacokinetics:
- Acid sensitive → Capsule (30 min before meal)
11
Q
Good manufacturing practice
A
- Consistent high quality
- Appropriate for their intended use
- Meet the requirements of the marketing authorisation/clinical trial authorisation
