Lab 6 Flashcards
One hemoglobin molecule contains ______ heme group; each heme group normally combines with one molecule of _______
4, Oxygen
The hormone _________ stimulates the bone marrow to produce RBCS, this hormone is secreted by the ______
Erythropoetin, Kidney
Old red blood cells are destoryed by the _______ system, which includes these three organs
Reticuloendothelial; Spleen, liver, bone marrow
Heme derived from hemoglobin, minus the iron, is converted into a different pigment, known as
Bilirubin
An accumulation of bilirubin can cause yellowing known as
Jaundice
Hematocrit
Ratio of packed cell volume to total blood volume
The molecule formed by the binding of oxygen to deoxyhemoglobin
Oxyhemoglobin
A hemoglobin molecule containing oxidized iron is called
Methemoglobin
A molecule formed from the combination of hemoglobin and carbon monoxide is
Carboxyhemoglobin
A general term for an abnormally low RBC or hemoglobin concentration
Anemia
The major phagocytic WBCs are called
Neutrophils
Molecules that activate the immune system are called
Antigens
WBCs leave capillaries by
DIAPEDESIS
Antibodies are produced by ______ lymphocytes, cell-mediated immunity is provided by ______ lymphocytes
B, T
The universal blood donor is blood type
O
The person most in danger of having a child who develops erythroblastosis fetalis is a woman who has the blood type _______ when her husband has the blood type ________
Rh negative, Rh positive
The factor that starts the extrinsic clotting pathway:
Tissue thromboplastin
Which clotting pathway is faster?
Extrinsic
The factor that coverts fibrinogen into fibrin is
Thrombin
What is thrombin derived from
Prothrombin
What vitamin is needed for the formation of some of the clotting factors?
Vitamin K
Citric acid (citrate) is an anticoagulant
Because it removes Ca2+, which is necessary for clotting
The general category of disorders in which a person’s clotting time is abnormally long
Hemophilia
In forming a platelet plug, platelets release ______, which make other platelets sticky!
ADP
Define Anemia
Low oxygen-carrying capacity of the blood caused by low RBC count or low hemoglobin concentration
Anemia will cause a person’s hematocrit to
decrease
Pernicious anemia is due to a lack of vitamin
B12
What hormone is responsible for the increased production of RBCs?
Erythropoietin
Define agglutinogen
A protein antigen found on the surface of RBCS
Agglutinin
An antibody to agglutinogen
