lab 3 Flashcards

1
Q

what is total body water?

A

the sum of all the water contained in the body compartments, including intracellular and extracellular

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2
Q

what is an index of short-term total body water change?

A

body weight

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3
Q

how can you monitor changes in the different compartments?

A

via dilution markers

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4
Q

what % of body weight is the total body water?

A

60%

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5
Q

what % of the body weight is the intracellular fluid

A

40%

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6
Q

what % of body weight is the extracellular fluid?

A

20%

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7
Q

what % of body weight is the interstitial fluid?

A

15%

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8
Q

what % of body weight is the plasma?

A

5%

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9
Q

what % of body weight is the transcellular fluid?

A

variable (fluid found in body cavities)

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10
Q

in new borns, are the body water spaces higher or lower than in adults? which space is the same as adults?

A

the body water is higher; the intracellular volume space is the same

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11
Q

what is intracellular fluid?

A

it is the fluid in all cells

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12
Q

what is the interstitial fluid

A

it is the fluid that immediately surrounds the cells but is also outside the blood vessels

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13
Q

what is the plasma volume?

A

it is the fluid volume within the vasculature

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14
Q

what is the transcellular fluid?

A

it is the fluid found in the body cavities (such as intraocular, CSF synovial, urine, bile, intestinal secretions)

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15
Q

how do you find the volume of plasma?

A

use a known amount of solute; the concentration of the solute - the amount of solute/concentration. measure the marker over time and extrapolate back to zero to find the instantaneous concentration

loss of dye during the time it is distributing can be problematic

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16
Q

what can be used to measure plasma volume?

A

evan’s blue.

17
Q

what can be used to measure extracellular water volume?

A

thiocyanate (KSCN)

18
Q

how do you find the extracellular water volume?

A

determine the volume by the equation

concentration of marker=amount/volume then substract the volume of plasma

19
Q

how do you calculate blood volume?

A

multiply the plasma volume by (100%-PCV)

20
Q

what do you use to measure total body water?

A

deuterated D2O or 40AAP

or dessication until dry

21
Q

how do you calculate the intracellular volume?

A

measure total body water via deuterated water and substract extracellular volume