Lab 3 Flashcards

1
Q

What are the three major substrates for energy production

A
  1. carbohydrates
  2. fats
  3. proteins
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2
Q

What are the 3 major substrates stored as in the body

A
  1. carbohydrates –> glycogen (liver and muscle)
  2. fat –> triglycerides (adipose tissue and intramuscular depots)
  3. protein –> bodily protein (muscle…)
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3
Q

What are the major sources of fuel for OXIDATIVE ATP production

A

fat and carbohydrates

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4
Q

what is not considered a major contributer to energy production during exercise… why

A

protein because your body burns carbs and fat first

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5
Q

when does the body increase its role for protein as a fuel source

A

conditions of muscle glycogen depletion

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6
Q

How do you monitor substrate utilization during exercise

A

indirect calorimetry

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7
Q

What does indirect calorimetry work

A

utilizes measurements of expired CO2 and O2to calculate respiratory exhange ratio (RER)

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8
Q

What is RER

A

espiratory exchange ratio
ratio of (VCO2/VO2)
can be used to estimate substrate utilization

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9
Q

how does RER estimate substrate utilization

A

b/c fats and carbohydrates use and produce different amounts of CO2 and O2

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10
Q

How to determine numbers for RER values

A

Every RER value ahs corresponding caloric equivalent for O2 and estimated contribution of carbs and fats to E contribution

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11
Q

What has to be known to calculate total energy expenditure

A

VCO2/VO2
(carbohydrate + fat)

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12
Q

given total energy expenditure what can be calculated

A

absolute amount of energy production from given substrate can be calculated

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13
Q

What does the mitochondria do in the cell for glucose

A

mitochondria can oxidize glucose at a much higher rate than free fatty acids

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14
Q

What happens when exercise intensity increases from mild, to moderate, to hard what is effected – known as what

A

relative contribution of carbohydrates becomes increasingly important

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15
Q

What is the crossover concept

A

exercise intensity increases and and increase in contribution of carbohydrate as energy source

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16
Q

due to adaptations with endurance trainings what happens to the crossover point

A

it will shift to the right on the graph of substrate utilization versus VO2max to a higher relative and absolute work rate

17
Q

In a untrained individual to a trained athlete how does the crossover experience differ

A

untrained indiviudal (50% CHO/ 50% fat) occurs at 30% VO2max
trained athlete will experience the crossover at about 40-50% VO2max

18
Q

Why does the delay in “crossover” exist

A

delay in the “crossover” from fats to carbs is advantageous due to conservation of limited glycogen stores

19
Q

what is important to differentiate for contributions of fat and carbs

A

differentiate between the absolute and relative contributions of fats and carbs at given work rate

20
Q

At low intensity what happens to the relative (%) contribution of fats…what happens to abs number of total calories –> what happens to absolute amount of fat oxidation

A
  • relative (%) contribution of fats is higher
  • abs number of total calories is lower
  • absolute amount of fat oxidation is lower (40% of 10kcal/min = 4kcal/min)
21
Q

At moderate intensity what happens to the relative (%) contribution of fats…what happens to relative number of total calories –> what happens to absolute amount of fat oxidation

A

relative (%) contribuations of fats is lower, absolute number of total calories is higher –> absolute amount of fat oxidation is higher

22
Q

oxygen consumption represents what

A

total energy expenditure during submaximal, steady-state exercise

23
Q

what happens as exercise intensity increases

A

VO2 and total energy expenditure increase linearly

24
Q

What is happening in this lab

A

3, 6-minute exercsie bouts on bicycle ergometer or treadmill at 3 incremental intensities with 5-minute break between each intensity

25
What is the RER for fat in this equation: C16H32O2 + 23O2 --> 16CO2 + 16H2O
R= VCO2/VO2 = 16CO2/23O2 = 0.7
26
What is the RER for carbs in this equation: C6H12O6+ 6O2 --> 6CO2 + 6H2O
R = 6CO2/6O2 = 1.0
27
what are the factos that determine fuel selection
1. intensity 2. duration 3. training status == higher oxidative capacity (crossover shift right (increase fat utilization [longer], increase mitochondrial density, increase capillary density, increase FFA transpo and oxidation, spare glycogen) 4. Diet (CHO supplementation)
28
if you increase intensity what happens to the carbohydrate contribution
increase CHO contribution
29
Where is the "fat burning zone"
oxidation of fat is highest at an exercise intensity of 50% VO2 max and lowest at 100% VO2max
30
as exercise duration increases what happens with fuel utilizaiton
FAT utilization increases and decrease in CHO utilization
31
If you have an acute diet manipulation how does it affect substrate utilization
consuming CHO before or during exercise INCREASES CHO utilizaiton and decreases FAT utilization
32
If you have an chronic diet manipulation how does it affect substrate utilization
- Consuming a high CHO diet increases CHO utilization during submax exercise - consuming high FAT diet increases FAT utilization
33
When is the best time to ingest CHO before exercise
fuel 2-4 hours before exercise
34
glucose inhibits what to make fats less available
glucose inhibits lipolysis
35