LAB 1 histology Flashcards
5 functions epithelium
- Protection
- Sensory function
- Secretion-glandular epithelium
- Absorption
- Extrection
3 steps to classify of covering and lining epithelia
- NUMBER OF CELL LAYERS
- one layer: simple epithelium. They are very thin, allow passage between lumen and tissues
- several layers: STRATIFIED epithelium: main function iis to protect tissue that they cover - SHAPE OF THE CELLS:
- flat: SQUAMOUS epithelium (nuclei are flat and parallel)
- square: CUBOIDAL epithelium (nuclei are oval and parallel)
- rectangular: COLUMNAR epithelium (nuclei are round and middle of the cell) - SPECIALIZATION OF THEIR CELL SURFACES (cilia, microvilli)
simple and stratified squamous
SIMPLE SQUAMOUS:
- Location: air sacs of lungs, blood vessels, kidney glomeruli, - Function: lubrification * * thinnest of all so good for diffusion, secretion, filtration
STRATIFIED SQUAMOUS
- thickiest of all the epithelium
- Location: skin, mouth..
- Lubrification, protection
- May contain keratin (skin) or not (wet surfaces such as vagina, tongue, esophagus..)
- thickiest of all the epithelium
simple, pseudostratified and stratified columnar
SIMPLE COLUMNAR:
- Location: stomach, intestines, uterus
- Function: protective, SA, secrete mucus
** non-ciliated: contains microvilli on the apical surface (increase surface area) so found in the digestive
Ciliated: found in the respiratory system, part of the uterus and uterine tubes
PSEUDOSTRATIFIED COLUMNAR:
- Location: trachea, fallopian, tubes - Role: movement * * cilia: trachea, upper respiratory * * non-cilia: male urethra
STRATIFIED COLUMNAR:
- Location: vas defense, male urethra - Function: support and some movement
simple and stratified cuboidal
SIMPLE CUBOIDAL:
- Location: ovaries, kidney tubules, thyroid glans - Role: secretion and absorption
STRATIFIED CUBOIDAL:
- Location: mammary glands, sweat glands - Role: secretion, absorption and protections
transitional epithelial
TRANSITIONAL
- Location: bladder - Role: stretch, protection against seepgae
exocrine vs endocrine glands
EXOCRINE GLANDS: discharge secretions into ducts (not going in the blood but outside)
Ex: salivary or sweat gland
ENDOCRINE GLANDS: ductless glands; discharge secretions directly into the blood or intestitial fluid
Ex: pineal gland, pituitary gland, thyroid gland, thymus, adrenal gland, pancreas, ovary, testis
types of glandular epithelium
- APOCRINE: product pinches off and is released from Apex
- Mammary glands
- Hair follicle sweat glands (at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the hair follicle; produce an odorless, oily, opaque secretion that gains its characteristics odor upon bacterial decomposition
- Goblet cells (in colon)
- HOLOCRINE: product collect in the cell, then when product is released the plasma membrane ruptures
Ex: sebaceous gland - MEROCRINE (or eccrine): secrete product through plasma membrane. Most common type
Ex: salivary gland, gastric glands, sweat glands in body acting in cooling system
functions connective tissue
Functions:
1. Binding, support and packaging 2. Protection, defense and repair 3. Insulation (by adipose tissue) 4. Transportation (blood)
General characterisics: ECM predominates in most connective tissues and determines its physical characteristics
Cells that secrete the extracellular matrix that is characteritsic of the tissue:
- Connective tissue proper: FIBROBLASTS
- Cartilage: CHONDROBLASTS
- Bone: OSTEOBLASTS
- Blood: hemocytoblast
** other things in the matrix: white blood cells, mast cells, macrophages, antibody…
4 types connective tissue
- FIBROUS (connective tissue proper)
- LOOSE (aerolar): ex: fascia, fat (protection and insulation) ** lots of fibroblasts, elastic fiber…
- DENSE REGULAR: ex: tendons and ligaments (flexible but strong)
- DENSE IRREGULAR: ex: symphysis pubis joint
- CARTILAGE (elastic- fibrocartilage- hyaline)
Gives firm but flexible support.
- Elastoc: ear, epiglottis
- Hyaline: trachea rings, joint surface of bone, larynx
- Fibrocartilage: symphysis pubis joint - BONE
- Compact bone
- Spongy bone - mineralized ECM - BLOOD
- Transportation and protection
3 types of fiber in the ECM of connective tissue
- COLLAGEN fiber: the thoughest, resist longitudinal stress
- ELASTIC fibers: can be stretched but retake their initial form. Found in lungs and blood vessels walls
- RETICULAR fibers: form a branching network suporting soft organs such as the liver and spleen
composition ground substance connective tissue
- INTERSTITIAL FLUID
- CELL ADHESION PROTEINS: all connective tissue cells to attch themselevs to the matrix elements
- PROTEOGLYCANS: where polysaccharides are attached
functions : support cells, bind them together and a medium for nutrients
cartilage
- a lot of collagen fibers, elastin fibec fibers and proteoglycan
- Differs from other tissue in that only one cell type is present: CHONDROCYTE
- LACUNAE house cells: lacuna hole or pit- is a small space containing a chondrocyte in cartilage or an osteocyte in bone
- Cartilage is avascular!!! Unlike other connective tissue, so repair more slowly
- a lot of collagen fibers, elastin fibec fibers and proteoglycan
(( ECM is secrete by chondroblasts foun din the outer covering layer of cartilage. As it secrete the ECM it become trapped inside it so it matures in chondrocytes
Hyaline cartilages exists on the ventral ends of ribs; in the larynx, trachea and bronch +articular surface of bones
role of bone tissue
- Support
- Protection
- Point of attachment for muscles
- Reservoir for muscles
- Supports blood-forming tissue