Lab #1 Flashcards
What does a neutrophil do
Kills bacteria by phagocytosis and respiratory burst, engulfs dying or dead cells
what does a lymphocyte do
produces a specific immune response by direct cell attack or via antibodies
(virus, bacteria or tumor)
What does a monocyte do
developed into phagocytic macrophage, triggers specific defences by presenting an antigen to T cells (think hungry bean)
(bacterial mostly)
What does a eosinophil do
releases enzyme to destroy parasites, decrease allergic response by engulfing antibody labled materials
(think eos lip balm don’t share bc parasite)
What does a basophil do
releases histamine to trigger an inflammatory response (allergic reaction) (think of a basil allergy)
what does a thrombocyte do
forms a plug to seal small tears in blood vessels, releases a chem. to stimulate blood clotting
Significance of RBC structure
- biconcave: can stack, increased surface area decreased diffusion distance
- spectrin proteins in PM hip with squeezing through capillaries
- filled with hemoglobin and mitochondria
Which ones are granulocytes
Basophil, eosinophil, neurotrophil
What are the components of plasma
- Nutrients: glucose, amino acids, fat, vitamins
- Gases: CO2, O2
- Wastes: lactic acid, uric acid, urea, creatinine
- Ions: Na+, K+, Ca2+, Cl- ect.
- Plasma proteins: albumin, hormones, clotting proteins, alpha, beta & gamma globulins ( made in liver)
Leuokcyte ranges (NLMEB)
N-50-70% L- 20-30% M- 2-8% E- 2-4% B- 0.5-1%
What increased levels of each would suggest
N-Bacterial infection, myelitis leukaemia, rheumatoid arthritis, stress
L-Lymphocytic leukaemia, infections mononucleosis, viral infection
M- Chronic inflammation, viral infection, tuberculosis
E- Allergies, parasitic infection, autoimmune disorder
B- inflammatory proceses, healing
What decreased levels of each lymphocyte would mean
N-Aplasic or pernicious anemia, viral infection, radiation
L- radiation, aids, corticosteroid therapy
M- aplastic anemia, corticosteroid therapy
E- steroid therapy
B- hypersensitivity reactions
what would be present during an allergy
basophil, eosinophil
what is leukaemia
cancer of stem cells
what is leukocytosis
increased WBC count
