L9 Mitosis and Meiosis Flashcards

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1
Q

Chromosome act as the vehicles that must…

A

Pass on genetic information accurately

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2
Q

Mitosis produces…

A

2 genetically identical daughter cells

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3
Q

Mitosis is the basis for asexual reproduction in…

A

Single-celled eukaryotes

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4
Q

In humans mitosis plays an important part in (4)…

A
  • Embryonic development
  • Skin cells
  • Wound healing
  • Reticulocytes (immature red blood cells)
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5
Q

Uncontrolled mitosis can lead to…

A

Tumor formation

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6
Q

In mitosis a cell goes from Xn to Yn which divides to form two Xn cells.

A
X = 2
Y = 4
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7
Q

The 5 phases of mitosis are:

A
  1. Prophase
  2. Prometaphase
  3. Metaphase
  4. Anaphase
  5. Telophase
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8
Q

The kinetochore is…

A

The protein at the centromere, which serves as an attachment point for the mitotic spindles

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9
Q

Spindle fibres are…

A

Microtubules running between the two poles of the cell, creating the axis for separation of the chromosomes

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10
Q

The centriole generates spindle fibres and has a (structure)…

A

9 triplet microtubule structure

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11
Q

Interphase is divided into 4 possible phases…

A
  • G0
  • G1
  • S
  • G2
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12
Q

Meiosis is the cell division which produces…

A

Gametes (sperm, egg cells, spores, pollen)

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13
Q

Unlike mitosis, meiosis results in (2)…

A

Haploid gametes (1n) and genetic variability

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14
Q

During meiosis I, genetic reassortment occurs through (2)…

A

‘Crossing-over’ and independent assortment

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15
Q

The chiasma is the…

A

Physical connection between non-sister chromatids during meiosis I

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16
Q

During interphase between meiosis I & II DNA replication ( occurs / does not occur / sometimes occurs )

A

Does not occur ❌

17
Q

Meiosis prophase I can be subdivided into 5 phases, these are…

A
  1. Leptonema (Leptotene)
  2. Zygonema (Zygotene)
  3. Pachynema (Pachytene)
  4. Diplonema (Diplotene)
  5. Diakinesis
18
Q

Meiosis I, prophase I - 1. Leptotene

A

Duplicated chromosome starts to condense

19
Q

Meiosis I, prophase I - 2. Zygotene

A

Synapsis begins. Synaptonemal complex forms, forming a ‘bivalent’ (a.k.a ‘tetrad’)

20
Q

Meiosis I, prophase I - 3. Pachytene

A

Synapsis completed. Crossing over occurs

21
Q

Meiosis I, prophase I - 4. Diplotene

A

Chiasma becomes visible. Synaptonemal complex begins to disappear

22
Q

Meiosis I, prophase I - 5. Diakinesis

A

The nuclear envelope fragments

23
Q

Meiosis II is similar to…

A

Mitosis

24
Q

The production of male gametes is continuous. In contrast, oogenesis pauses at prophase I in the embryo, resuming…

A

Prior to ovulation (years later)

25
Q

Aneuploidy

A

Chromosome number is not an exact multiple of the haploid number

26
Q

Non-disjunction results in aneuploid gametes. Non-disjunction is…

A

The failure of chromosome pairs to separate

27
Q

Trisomy is a polysomy with…

A

Three chromosomes 3️⃣

28
Q

Trisomy 21 results in…

A

Down Syndrome

29
Q

The centrosome is comprised of…

A

A pair of centrioles

30
Q

When does crossing over occur?

A

Prophase I

31
Q

Why is crossing over important?

A

To increase genetic diversity