L7-Homeopathy Reflections Flashcards

1
Q

State the 3 contributing factors of Evidence Based-Medicine Paradigm. Describe each briefly.

A
  1. Best evidence
  2. Clinical expertise
    - Professional judgement
    - Experience
  3. Pt values
    - Religious &moral beliefs
    - Preference
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2
Q

What is the Law of Minimum Dose?

What is another name for it?

A

-AKA: Law of Infinitesimals
􏰁-Minimum dose required to make a reaction in the body
􏰁-Dilution w/ succussion (shaking) to potentize a crude drug
􏰁>Mother Tincture (Q)
􏰁>Safety of Minimum Dose

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3
Q

Law of Minimum Dose.

What is homeopathic 5C?

A

Amount of the substance is at picogram level

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4
Q

Law of Minimum Dose.

1 in a ___ chances of finding A SINGLE molecule in the final product when the potency is 17C.

A

trillion

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5
Q

Law of Minimum Dose.
In order of for a 30C product to contain 1 molecule of the original substance would require a container of water ____x the size of earth

A

30 billion

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6
Q

Law of Minimum Dose.
What is Anas Barbariae Hepatis & Cordis Extractum?
What is it used for?

A

-this is a common thing to use for flu; contains:
Anas barbariae hepatis: duck liver
Cordis extractum: duck heart
-> freshly killed and incubate for 60d and then go through serial dilutions
-this product has $20mill in profit

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7
Q

Law of Minimum Dose.

IF DILUTED SO HEAVILY, how do homeopaths explain the therapeutic effects of their products?

A
  1. Memory of water lol
  2. Nanoparticles LOL
  3. Hormesis
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8
Q
  1. Memory of Water.

Describe.

A
  • Clathrates: water clusters - how properties of homeopathic dilution can be “transferred” to vehicle solvent
  • Gecker and Samal: particles dissolved in polar solvent clustered into aggregates 5-10x bigger than in the original solution
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9
Q
  1. Memory of Water.

Is this a probable theory?

A

NO lol

  • while there is truth to the formation of patterns, very improbable that it will hold once you get up to the large amount of dilutions
  • also note: nothing is still nothing..
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10
Q
  1. Nanoparticles.

Describe.

A
  • particles between 1 and 100 nanometers in size
  • in nanotechnology, a particle is defined as a small object that behaves as a whole unit with respect to its transport and properties
  • 0.05-200pg in 1 drop of liquid dose
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11
Q
  1. Hormesis.

Describe.

A

-Hormesis: stimulatory effects (i.e. body will try to fight it off) caused by a small amount of toxin substances.
>& if you give anything more then your body starts to fail.

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12
Q
  1. Hormesis.

Is it plausible?

A
  • Nah

- Homeopathic medication diluted so aggressively, it may not even contain med - i.e. nothing to fight off.

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13
Q

Research.

Describe the research that has gone in to proving the efficacy of Homeopathy.

A

-200 years of study
-well-articulated practice theory
>philosophy is NOT proof!! (just like basic pharmacology is not straight proof)
-case report based clinical literature
-high levels of patient satisfaction
-growing modern research base

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14
Q

Research.
Describe the “Hierarchy of Evidence”.
(from best to worst)

A

1) meta analysis of RTCs
2) individual RCT
>we want the above 2!!!
3) observational studies (patient important outcomes)
4) Basic research (test tube, animal/human phys)
5) clinical experience (non-systematic clinical observation)

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15
Q

Study 1: “Effectiveness, safety and cost-effectiveness of homeopathy in general practice”.
Describe:
1. Purpose &
2. Results of the research study.

A

-Purpose: validate homeopathy by hompeopathic drs
-Results: validated by clinical evidence & regarded as safe.
>reliable statements of cost-effectiveness N/A

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16
Q

Study 1: “Effectiveness, safety and cost-effectiveness of homeopathy in general practice”.
3. Describe the problems w the references of this study.

A
  1. Non-systemic narrative reviews
  2. Often have non-conventional stats
    >concludes HQ studies more likely to be neg (more HQ studies needed)
  3. Old trials
  4. False claims
  5. Faked data
  6. Picked topic that was hard to define/based on self-reporting.
  7. “Individualized” tx (basically just a bunch of randy STOOF)
17
Q

Study 1: “Effectiveness, safety and cost-effectiveness of homeopathy in general practice”.
4. What is the importance of this study?

A

-Referenced by most research journals.

18
Q

Study 1: “Effectiveness, safety and cost-effectiveness of homeopathy in general practice”.
5. List 2 of the “therapies” used in this study.

A
  1. Mercurius vivus: quicksilver, metallic mercury

2. Arsenicum album: arsenic trioxide

19
Q

Study 1: “Effectiveness, safety and cost-effectiveness of homeopathy in general practice”.
Describe the problems with Mercurius vivus.
(hint: 1. Mind, 2. General, 3. Stool).

A
  1. Mind: Slow, lethargic, weakness of memory (basically match up the tox sx w those that the pt is displaying)
  2. General: Chills alternating with heat, profuse perspiration. Worse in evening and night. Profuse salivation, offensive breath, indented tongue. Violent thirst for cold drinks; worse in evening until midnight.
  3. Stools: Slimy, scanty, lienteric, bloody. Acrid ,corrosive, frothy, yellow. Sour odor.
20
Q

Study 1: “Effectiveness, safety and cost-effectiveness of homeopathy in general practice”.
Describe the problems with Arsenicum album.
(hint: 1. Mind, 2. General, 3. Stool).

A
  1. Mind: Great anxiety and restlessness. Tossing about in bed. Fearful doesn’t want to be alone.
  2. General: Prostration. Worse after midnight. Burning heat with thirst for small amounts. Chilly, better being covered, cold sweats. Vomiting immediately after eating or drinking.
  3. Stools: Acrid, burning, excoriating. Diarrhea worse at night, after midnight. Putrid, bloody, odor of rotten
21
Q

Research.

OUR conclusions of “evidence-base” for homeopathy.

A
  1. limited evidence - at best mixed
  2. meta analysis - limits
  3. more rigorous trials tend to yield smaller effects
  4. publication bias
  5. cochrane reviews= standard and even they have said that we cannot conclude that they have benefit (no effect beyond placebo)
22
Q

Homeopathic product regulations all around the world!

1. How does Canada (Health Canada) regulate this ish?

A
  1. Must have DIN-HM
    >but this really means nothing as at one point even red bull had one
  2. Limits to products (pharmacopeia)
  3. 12C or greater for certain products
    >i.e. must have something in it LOL
  4. homeopathic use is acceptable evidence
23
Q

Homeopathic product regulations all around the world!

2. How does the US (FDA) regulate this ISH?

A
  • FDA approval safe and effective
  • focuses on safety BUT their philosophy overall is for freedom and choice
  • after 1970 they basically said that no products were killing anyone so they didnt really want to be involved
24
Q

Homeopathic product regulations all around the world!

3. How does the UK (National Health Service) regulate this ISHHHHH?

A
  • NHS funds homeopathic remedies in the UK
  • controversial
  • boots subject of protest
  • pressure to have funding removed
25
Q

T/F: Canada does NOT fund homeopathy.

A

TRUE! - phew

-Not cost effective.

26
Q

LAST TOPIC - SAFETY!

Are we concerned?

A
  • not really..
  • DI’s (hypothetically BUT there is nothing there so nothing to interact with)
  • safety of minimum dose
  • adulterants - safe manufacture
  • however also take into the fact that they may be taking this instead of an actual product that may be beneficial for them
27
Q

LAST TOPIC - SAFETY!

When may homeopathic meds not be appropriate?

A
  1. Malaria
  2. Tx/Px of AIDS
  3. Instead of vaccines
  4. Tx of cancer
28
Q

Is it important to keep an open mind?

A

Yes and no.

-Give accurate info as well as take respect pt autonomy.