L6 Renal function Flashcards
Kidney hormones
Erythropoeitin
Renin
1,25 dihydroxyvitamin D (Calcitrol)
Erythropoeitin (EPO)
Acts in bone marrow to stimulate synthesis of new erythrocytes
1,25 dihydroxyvitamin D
regulation of calcium absorption
End stage renal disease and oral cavity steps
Cant get rid of excess nitrogen
Converted to ammonium
Blood is alkalized
Increase oral pH
Contraindications for End stage renal disease patients
nephrotic drugs: tetracyclin, acyclovir, aspirin, NSAIDS
Increased susceptibility to bleeding due to destruction of platelets
Filtration steps
Cortex: -Blood filtered in glomeruli -Pass thru nephron tubules Medulla: -Concentrate and collect urine Renal pelvis, ureter, bladder, urethra
blood leaving the glomerular capillaries flows into
vasa recta
Renal corpuscle contents
Glomerulus
Renal capsule
blood flow thru glomerulus is regulated by
Smooth muscle contraction in afferent and efferent arterioles
Resonse of juxtaglomerular apparatus
Sympathetic nervous system
Renin is secreted by
Juxtaglomerular apparatus
Juxtaglomerular apparatus location
intersection of macula densa of distal tubule and afferent/efferent arterioles
Proximal tubule reabsorption
Salt/water
glucose
amino acids
2/3 salt/water
All glucose
All amino acids
regulation of Calcium happens in
Distal convoluted tubule
Collecting duct
extent
Regulates
Extends from cortex thru medulla
Sodium, potassium, water
Renal clears ance be used to measure Glomerular filtration rate based on
1: substance must be freely filtered
2: substance is not secreted
3: substance is not reabsorbed