L6 Renal function Flashcards

1
Q

Kidney hormones

A

Erythropoeitin
Renin
1,25 dihydroxyvitamin D (Calcitrol)

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2
Q

Erythropoeitin (EPO)

A

Acts in bone marrow to stimulate synthesis of new erythrocytes

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3
Q

1,25 dihydroxyvitamin D

A

regulation of calcium absorption

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4
Q

End stage renal disease and oral cavity steps

A

Cant get rid of excess nitrogen
Converted to ammonium
Blood is alkalized
Increase oral pH

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5
Q

Contraindications for End stage renal disease patients

A

nephrotic drugs: tetracyclin, acyclovir, aspirin, NSAIDS

Increased susceptibility to bleeding due to destruction of platelets

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6
Q

Filtration steps

A
Cortex: 
-Blood filtered in glomeruli
-Pass thru nephron tubules
Medulla:
-Concentrate and collect urine
Renal pelvis, ureter, bladder, urethra
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7
Q

blood leaving the glomerular capillaries flows into

A

vasa recta

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8
Q

Renal corpuscle contents

A

Glomerulus

Renal capsule

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9
Q

blood flow thru glomerulus is regulated by

A

Smooth muscle contraction in afferent and efferent arterioles
Resonse of juxtaglomerular apparatus
Sympathetic nervous system

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10
Q

Renin is secreted by

A

Juxtaglomerular apparatus

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11
Q

Juxtaglomerular apparatus location

A

intersection of macula densa of distal tubule and afferent/efferent arterioles

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12
Q

Proximal tubule reabsorption
Salt/water
glucose
amino acids

A

2/3 salt/water
All glucose
All amino acids

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13
Q

regulation of Calcium happens in

A

Distal convoluted tubule

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14
Q

Collecting duct
extent
Regulates

A

Extends from cortex thru medulla

Sodium, potassium, water

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15
Q

Renal clears ance be used to measure Glomerular filtration rate based on

A

1: substance must be freely filtered
2: substance is not secreted
3: substance is not reabsorbed

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16
Q

Normal glomerular filtration rate

A

Male: 90-140 ml/min
Female: 125 ml/min

17
Q

Glomerulus structure

A

Fenestrated capillaries with podocytes forming filtration slits

18
Q

Size for freely filtering vs not

A

Free: less than 20A

Not filtered: More than 42A

19
Q

Charge that is hard to filter

A

negative becasue negative lamina dura

20
Q

Starling forces

A

pressure differences in blood in capillaries and fluid in capsule

21
Q

Autoregulation mechanisms

A

Myogenic mechanism: vascular smooth muscle contracts when stretched
Tubuloglomerular feedback: JGA adjusts afferent arteriole diamter