L12 GI Flashcards

1
Q

Four main hormones in digestion

A

Gastrin
Cholecystokinin
Secretin
Glucose dependent insulinotropic peptid

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2
Q

Phases of GI

A

Cephalic
Gastric
Intestinal

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3
Q

Cells of gastric pit

A

Mucous neck cells
Chief cells
Parietal cells

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4
Q

Glandular areas

A

Oxyntic:body and fundus
Pyloric: antrum

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5
Q

HCl secretion

A

Parietal cells in fundus and body

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6
Q

Intrinsic factor secretion

A

Parietal cells in fundus and body

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7
Q

Pepsinogen secretion

A

Chief cells in body and antrum

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8
Q

Secretion of HCl

A

CO2 H2O CA make HCO3 and H
Cl in, HCO3 out (blood)
Hout/Kin atpase
Clout, combines with H in lumen

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9
Q

Inputs to parietal cells for HCl

A

Histamine is strongest

Gastrin and Ach trigger Histamine and have direct effects

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10
Q

Somatostatin mechanism

A

Secreted by D cell
inhibits gastrin by G cell (histamine indirectly)
Inhibits Parietal cell directly

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11
Q

When Chyme drops below pH 3, what happens

A

Secretin is produced

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12
Q

Enterogastrones

A

Secretin and CCK

Inhibit secretion and motility in stomach

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13
Q

CCK is stimulated by and leads to

A

amino acids
Fatty acids
Leads to Pancreas enzymes
Bile flow from gallbladder

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14
Q

Secretin is stimulated by and leads to

A

High H+

Leads to pancreas HCO3

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15
Q

Peristalsis is driven by

A

myoelectric complex

Motilin hormone

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16
Q

Primary purpose of Large intestine

A

Na reabsorption