L10 Flashcards
Stensons
Whartons
Rivinus
Parotid: serous
Submandibular: mixed
Sublingual: mucous
Von ebner glands
Function
Involved with taste (rinse circumvallate and foliate papillae
Secrete lingual lipase for fatty acid digestion
Saliva initiates digestion of
Starch
Fat
Most of the minor salivary gland are ___ except for___
Mucous
Except for Von Ebners
Salivon structure
Acinus (serous, mucous)
Intercalated duct
Striated duct
Excretory duct
Salivary fluid secretion Na Cl K Ca
2Kin/3Na.out Na/K/2Cl.in Intracell Na is low Intracell K is high Intracell Cl is high Activation from Ca opens Kout, Clout Na follows paracellularly Cl in lumen
Alternalive mechanism for secretion
CO2 in Converted to HCO3 HCO3 pushed out, Cl pumped in Cl pumped out to lumen OR HCO3 from1st step pumped into lumen
Primary secretion and secondary modification
Acini: H2O permeable w/ primary secretion
Ducts: H2O Impermeable w/ secondary modification (reabsorption of salutes)
Secondary secretion composition
High rate
Low rate
Hypotonic (opposed to isotonic primary)
Low rate: high [K]
High rate: high [Na]
Most abundant protein in salia
Mucin
Amylase
Function
Location
Produced by parotid
In zymogen
Breakdown of starch
Innervation of salivary glands
VII: Submand. Subling
IX: Parotid
Neuros in salivation
Para: ACh
Symp: Norepinephrine
Parasympathetic stimulation steps
Ach binds to Muscarinic Gprotein activates PLC Produce IP3 Ca Released Cl channel activated Na and H2O follow
Sympathetic stimulation steps
NE binds to Beta adrenergic receptors AC cAMP PKA Phosphorylation that leads to transciption?
