L2 Flashcards

1
Q

Lung compliance

A

Change in lung volume for a given change in pressure

Inverse of stiffness

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2
Q

Pressure and surface tension

A

P = 2St/R

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3
Q

Two factors of compliance

A

lung elasticity

surface tension

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4
Q

Surfactant effects

A

increase compliance, decrease surface tension

Greater effect on smaller alveoli

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5
Q

How is surfactant production regulated

A

stretch receptors on type II cells increase production

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6
Q

Asthma treatment

A

glucocorticoid or bronchodilators

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7
Q

Decrease compliance effects

A

Faster, shallow breathing

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8
Q

Emphysema

A

alveolar tissue damaged due to overproduction of proteolytic enzymes

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9
Q

Tidal volume
Inspiratory reserve volume
Expiratory reserve volum
Residual volume

A

TV: entering lungs per breath: 500
IRV: Max volume inspired: 3000
ERV: V exhaled beyond TV: 1500
RV: V in lungs after max exhalation: 1000

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10
Q

Vital capacity

A

IRV + ERV + TV 5000

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11
Q

Total lung capacity

A

Vital capacity + residual volume 6000

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12
Q

Obstructive lung disease vs restrictive lung disease

A

OLD: Decrease forced expiratory volum in 1 second, normal Vital capacity
RLD: Normal forcredd expiratory volume in 1 second, decreased vital capacity

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13
Q

Venilation

A

Tidal volume X respiratory rate

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14
Q

Alveolar ventilation

A

(Tital volume - dead space) x resp. rate

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15
Q

Steps of respiration

A
ventilation
external respiration
gas transport
internal respiration
cellular respiration
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16
Q

Daltons law

A

total pressure is the sum of individual pressures

17
Q

Henry’s law

A

amount of gas dissolved in liquid is proportional to partial pressure

18
Q

Alveolar PO2 is determined by

A

Atmospheric O2
Rate of Alveolar ventilation
Rate of cellular O2 consumption

19
Q

Surfactant composition

A

Phsopholipid

Protein

20
Q

What is most important in determining compliance

A

overcoming surface tension