L2 Flashcards
Lung compliance
Change in lung volume for a given change in pressure
Inverse of stiffness
Pressure and surface tension
P = 2St/R
Two factors of compliance
lung elasticity
surface tension
Surfactant effects
increase compliance, decrease surface tension
Greater effect on smaller alveoli
How is surfactant production regulated
stretch receptors on type II cells increase production
Asthma treatment
glucocorticoid or bronchodilators
Decrease compliance effects
Faster, shallow breathing
Emphysema
alveolar tissue damaged due to overproduction of proteolytic enzymes
Tidal volume
Inspiratory reserve volume
Expiratory reserve volum
Residual volume
TV: entering lungs per breath: 500
IRV: Max volume inspired: 3000
ERV: V exhaled beyond TV: 1500
RV: V in lungs after max exhalation: 1000
Vital capacity
IRV + ERV + TV 5000
Total lung capacity
Vital capacity + residual volume 6000
Obstructive lung disease vs restrictive lung disease
OLD: Decrease forced expiratory volum in 1 second, normal Vital capacity
RLD: Normal forcredd expiratory volume in 1 second, decreased vital capacity
Venilation
Tidal volume X respiratory rate
Alveolar ventilation
(Tital volume - dead space) x resp. rate
Steps of respiration
ventilation external respiration gas transport internal respiration cellular respiration