L3 Flashcards

1
Q

Loading and unloading phase

A

Loading: plateau
Unloading: steep region

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2
Q

Shifts curve right

A

Increase temp
Increase CO2
Increase H
Increase 2,3 DPG

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3
Q

Normal values for Hb

A

15 grams

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4
Q

Normal values for O2

A

20ml/100ml blood

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5
Q

Forms of CO2

A

dissolved: 7%
Hb bound: 23%
HCO3 (70%)

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6
Q

CO2 binds to form

A

Carbaminohemoglobin

Binds to heme portion, no competition with oxygen

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7
Q

CO binds to form

A

Carboxyhemoglobin

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8
Q

Carbonic anhydrase
What does it do
Where is it found

A

Catalyzes the formation of carbonic acid
Found in erythrocytes not plasma
Reaction acidifies the plasma

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9
Q

H binding

A

binds to histidine residues

Affinity depends on Po2 (Inverse)

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10
Q

How is H transported

A

Hb picks up H in tissues to minimize HCO3 effects on ph

Hb releases H in lungs to combine with HCO3 and CA runs reverse reaction

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