L6 Hypersensitivity Flashcards

1
Q

Immune responses that cause tissue injury are called?

diseases caused by these are called?

what do they arise from?

what classes?

A
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2
Q

Mechanisms of Hypersensitivity

Types?

description?

A
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3
Q

Type 1 hypersensitivity

what is it and what is it caused by?

triggered by what type of Ag?

if someone is Atopic what does that mean?

A
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4
Q

hypersensitivity type I

Mast cell mediators?

the most important ones?

Their roles?

A
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5
Q

Initial allergen encounter

start to binding of mast cell

A
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6
Q

Subsequent allergen encounters

A
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7
Q

Type I

sequence of events

A
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8
Q

The phases through the Type I response

what they cause?

timing?

A
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9
Q

Type 1 disease

Local reaction

what is it?

caused by?

What mechanism?

what else can cause it?

A
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10
Q

Type 1 disease

Systemic reaction

what cause this?

results in?

A
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11
Q

Allergen testing

What type does it test for?

often performed where?

what is a positive reactions?

A
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12
Q

Allergen-SIT?

What do you do?

what does it cause?

What else plays a role?

A
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13
Q

Type II hypersensitivity?

What cells play a role?

A
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14
Q

Diseases of Type II hypersensitivity?

A
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15
Q

Different effector mechanisms of Type II

A
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16
Q

Effector mechansims Type II

A.

B.

C.

17
Q

Type III hypersensitivity

what are they?

induce what?

major mechanism?

18
Q

Diseases of Type III hypersensitivity

Human diseases caused by what?

injury caused by?

19
Q

Effector mechanisms Type III

20
Q

Type IV hypersensitivity

Major triggers?

Tissue injury by?

21
Q

Diseases of Type IV hypersensitivity?

what plays dominant role in causing tissue injury?

Autoimmune diseases mediated by type IV?

Inflammatory diseases?

22
Q

Type IV hypersenstivity

called what?

caused by what?

tissue injury by what?

chronic or acute?

autoimmune diseases caused by?

also cause this?

23
Q

Delayed-type Hypersensitivity?

time?

PPD?

DTH reaction senstive?

24
Q

Contact dermititis

Poison ivy

25
Q

Allergic contact dermititis

What type of exposure?

type of hypersensitivity?

most common contact allergen?

26
Q

Granulomatous inflammation?

What is it?

What cell types?

creation of granulomas how?

27
Q

what a mature granuloma looks like?

28
Q

Mature granuloma formation

Time?

formation how?

29
Q

Systemic Lupus Erythematosus

Type of Hypersensitivity?

clinical manifestation?

Auto-Abs?

which cause?

Diagnostic test?

30
Q

Rheumatoid ARthristis

Type of hypersensitivity?

cells involved?

diagnostic test?

31
Q

Multiple Sclerosis

Type of hypersensitivity?

what happens?

32
Q

Type 1 diabetes mellitus

type of hypersensitivity?

what happens?

33
Q

Inflammatory bowel disease?

type of hypersensitivity?

34
Q

Role of (. ) in inflammatory bowel disease?

35
Q

Principles of immunotherapy