L5 - ASC

Question 1

eg of types of ASCs

Answer 1

haematopeitic
Mesenchymal
intestinal
neural

Question 2

what does the HSC divide into

Answer 2

ST-HSC

Question 3

where do HSC come from during the development of embyro

Answer 3

blood islands in the yolk sac

Question 4

after generating HSC from the yolk sac, where will it generate after

Answer 4

aorta-gonad mesonephros (AGM) at the ventral wall of the dorsal aorta

Question 5

how does the SC become generated from the dorsal aorta

Answer 5

the endothelium of the aorta undergo a change where it becomes round non adherant cell type

Question 6

types of Mescenchymal stem cells (MSC)

Answer 6

stromal

parenchymal

Question 7

function of stromal cells

Answer 7

provide support to the parenchymal cells

Question 8

function of parenchymal cells

Answer 8

provide the main function for that tissue

Question 9

example of stromal cells

Answer 9

multi potential bone marrow stromal cells

- used as a feeder layer for HSC in vitro

Question 10

what can multi potential bone marrow stromal cells differentiate into

Answer 10

osteoblasts > bone
adipocytes > fat
chondrocytes > cartilage

Question 11

where are the MSC found

Answer 11

in the perivascular cells surrounding the blood vessel