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B.3 > L.34 Enteral dosage form > Flashcards

L.34 Enteral dosage form Flashcards

1
Q

pharmaceutical dosage form butuh additive material ber pH

A

additive materal yang netral

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2
Q

benefits pharmaceutical dosage form untuk ingradeint dan palate

A

melindungi ingrediant, menutupi rasa pahit

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3
Q

enteral dosage from ada 2 bentuk dari tempat masuknya

A

oral, rectal

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4
Q

oral ada

A

sulingual, , , ,

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5
Q

physical form of dosage form

A

solid, liquid

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6
Q

solid ada

A

powder/pulveres
tablet (compress, coated, slow release)
kapsul
suppositories

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7
Q

liquid form ada

A

…

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8
Q

kaplet

A

tablet berbentuk kapsul

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9
Q

effervescent

A

kapsul yang sssssss sss

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10
Q

powder advantage

A

bisa untuk anak dan ortu yang tidak bisa nelen

lebih mudah menyesuaikan dosis

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11
Q

powder disanvantage

A

tidak stabil dalam air
rasa pahit dan bau
harus diminum pakai air putih

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12
Q

powder ciri

A

rapid onset
limited…?
large surfa area?

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13
Q

tablet kompress ciri

A

chewavle, efefrvescent, sulingual, buccal, lozenges, odt

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14
Q

coating tablet jenis

A

sugar coated, enteric? coated, film coated

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15
Q

ciri compressed tablet

A

oval/ flat round
poorly absorbed
difficult to swalloe
di dalemnya ada lebih dari 2 medicine?

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16
Q

chewable tablet

A 
quickly absorbed
good taste
local effect: antacid
systemic: antibiotics, vitamin
not suitable for ppl with no teeth
suitable for mobile ppl
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17
Q

effervescent tablet

A

systemic effect

contain effervescent salt

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18
Q

buccal tablet

A

absorption via buccal mucosa

bypass 1st pass metabolism

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19
Q

buccal tablet adv

A

rapid,

high bioavailaility

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20
Q

buccal disan

A

tidak nyaman di mulut

hanya bisa deliver small dosage

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21
Q

sublingual tablet

A

under tongue
bypass 1 pass metab
ISSD for heart

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22
Q

sublingual tablet adv

A

rapid onset, 5 min

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23
Q

lozenger/trochess ciri

A

efek hanya lokal (anaesthetic / antibiotik lokal)
praktis
yng populer punya funky shape

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24
Q

Orally disintegrating tablet ciri

A

small, easily broken filler

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25
Q

Orally disintegrating tablet adv

A

highly soluble
ga butuh air anyak
cocok buat pediatric n geriatric, impaired swallowing, ginjal impairment
contoh: zinkid

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26
Q

sugarcoated tablet/ dragee

A

untuk protection agains airborne, moisture, sunlight particle
umpleasant taste
slow release?

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27
Q

film coated tablet

A

compressed tablet coated with think insoluble polymer

untuk?

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28
Q

enteric coated tablet

A

tidak hancur di lambung tp ancur di usus
karena iritasi lambung (aspirin
protects the drug dari asam lambung (erythromycin)

29
Q

enteric coated jangan

A

tidak diberikan separuh ya!! harus terbungkus utuh, gabole dipecaha atu dikunyah

30
Q

slow release tablet

A

slow and susained release over a period of time agar konsentrasi di darah konstan
consist of 2/3 layer, rilis tiap layer dikit” tiap 12-8 jam

31
Q

slow release tablet adv

A

sustained concentration dan actuin
frekuensi konsumsi turun
efektif, side effect turun

32
Q

slow release talet disan

A

mahal
dosis tidak bisa fleksibel, gaisa dipersonalized
manufacturing failure -> overdosis!

33
Q

slow release talet

A

jangan dikunyah atau dipecah dosis udah berlipat

34
Q

soft capsule

A 
elastic shell (gelatin with alcohol/glyverin and sorbitol)
penyimpanan lama-lama jadi keras
35
Q

hard capsule

A

higroskopis, lama-lama lunak

isi powder granule

36
Q

hard capsule adv

A

mask taste and color
dissolve in gastric juice
tasteless

37
Q

hard capsule disad

A

difficult to swallow

mudah lunak kalau penyimpanan lembab

38
Q

ss garfik kapsul

A

kapsul, tablet, slow release kapsul, slow release tablet

39
Q

suppositories

A

buat delivery ke body orifices where they soften/dissolved

40
Q

rectal suppositories

A

systemic, local effect

act rapidly, no 1st pass metab

41
Q

vaginal suppositories

A

local only

42
Q

rectal suppositories disad

A

uncertain absorption, local irritation

43
Q

rectal suppositories kalo

A

pasien unconscious, muntah”, uncooperative, kejang (IV akal susah)

44
Q

perhatikan apa sebelum mau kasiin liquid dosage form?

45
Q

solution

A

jernih (faster asorption, homogen)

bisa dengan atau tanpa pemanis/perasa/warna

46
Q

solution adv

A

suitable for kids

47
Q

solution disad

A

large volume required

48
Q

suspensi

A

turbid, drug thats not solubele

with suspensor

49
Q

suspensi disad

A

absorption

50
Q

emulsion

A

oil in water or vice versa
turbid
sweeteer/ falvaor with or withour

51
Q

emulsion -

A

air sama oil misah kalau udah lama

52
Q

medicated syrup

A

concentrated

mengandung sugar/its sustitute

53
Q

medicated syrup +

A

asorbsi lbh cepet dr solid
pleasant taste
suitale for kids

54
Q

medicated syrup -

A

inaccuracy dosage

55
Q

dry syrup

A

unstable kalo di liquid form
liquid form 7 hari di room temp, 14 hari di refri
harus dikasih akuades dulu

56
Q

elixir

A

10-17 % alkohol sg pengawet, pelarut bahan aktif

palatable, tidak begitu kental

57
Q

elixir advantage

A

insolubke drug masuk ke hydroalcohol

less viscous

58
Q

elixir -

59
Q

oral drop

A

cocok untuk ayi

manis

60
Q

garfik penyerapan bentuk

61
Q

theophylline dan entuk konsentarsi

62
Q

journey menuju bzlood

63
Q

klasifikasi perizinan obat

64
Q

question 1

A

anticonvulsant: rectal
antipyretics: drop, syrup, enteric coated (kalo obatnya dikasih setahunan)

65
Q

q2

66
Q

q3

A

elixir sama dgn solution

syrup bisa suspension jd tergnatng bentuknya

67
Q

q4

A

sugar coated tablet

68
Q

kaplet dan kapsul, lebih lama mana?

A

kaplet. kapsul kan isinya powder, begitu luarnya benyek udah bisa cepet diserap

B.3 (14 decks)

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