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B.3 > L14 > Flashcards

L14 Flashcards

1
Q

hepatitis b clinical sign

A

not spesifik
jaundice, dark urine, clay color stool
hepatomegaly

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2
Q

akut hepatitis B

A

iasanya di bayi, gaada manifestasi klinis

makin tua makin kelihatan symotomnya

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3
Q

hepaiti B kronis

A

punya hbs Ag leih dari 6 bulan

kebanyakan lifelong

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4
Q

symptom hepatitis b kronis

A

..

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5
Q

epidemiologi hbv

A

most common

mayoritasa asia afrika

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6
Q

seroprevalence HBsAg

A

high: subsahara afrika, east asua, pasifik silanda, amaon basin

tengah central america, nort aerica, west eropa

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7
Q

transmisi hbv

A

vertikal, horiontal

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8
Q

vertical transmission

A

HBeAg +, transmisi 90%

HBsAg + HBeAg - : 10%

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9
Q

horizontal

A

sexual intercouse, pemakaian jarum suntik bersama

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10
Q

feature of hepatitis b virus

A

envelope

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11
Q

nukleotida

A

one partial dsDNA
core protein (HcAg)
hepatitis e antigen (HBeAg)
dna pol

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12
Q

S protein gene dimana

A

large orf

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13
Q

selain produksi virior, host juga akan produksi

A

subviral particles

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14
Q

subviral partikel tu

A

host derived lipoportein

envelope glyco protein

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15
Q

subviral: viral

A

1000-10.000:1

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16
Q

fungsi subviral particle

A

proteksi viral particle dari antibodi

17
Q

subtipe virus hepatitis b

A

ga pengaruh ke imunologi, kalo terinfeksi 1 maka yg lain juga bisa imun

18
Q

korelasi viral load?

A

gada korelasi dgn severity

19
Q

korelasi severity dgn

A

repon host cell

20
Q

HBsAg +

A

infectiors

21
Q

anti Hs Antibody +

A

imuniyas

22
Q

HBeAg+

A

highly infectious

23
Q

antiHBe +

A

mau selese infeksinya

24
Q

hepatitis C virus epidemiology

A

worldwide
before scrrening of blood: transfusion associated
diatas 15 th

25
Q

reinfeksi?

A

yes. abis terinfeksi ga njamin ada imunitas

26
Q

virion morphology HCV

A

spike like projection

genom: plus tsrand RNA

27
Q

genom HBC

A

heterogen,

no serotypic classif

28
Q

atogenesi mengenai kesembuhan

A

30%
70%
15-30% dari kronic hcv cirrhosis

29
Q

HCC mechanism

A

unknown

30
Q

reinfection?

A

yes

31
Q

marker hcv

A

HCV Ab denan 2nd 3rfELISA, se

..?

32
Q

hepatitis d

A

blood borne dlm etuk viroid

33
Q

genom

A

ssRNA viroid, deivut delta agent

34
Q

defective viru, gmn

A

gabisa infeksi sendirian. aru bisa ineksi kalo bersama HBV

35
Q

kenapa defective

A

perlu HBsAg coating baru bisa infeksi

B.3 (14 decks)

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