L3 Proteins Flashcards
Open chain amino acids(aliphatic)
Glycine and alanine
Aromatic amino acids
Phenylalanine and tryosine
Tryptophan
Semi essential amino acids
Histdine and arginine and inc in periods such as growth
What amino acid is replaced with which amino acid in sickle cell aneamia
Polar gultamate with non polar valine
What does amphoteric mean
In a solution amino acids can behave as acids and alkalis due to presense of acidic group (COOH) or basic group (NH2)
Whats a zwitterion
Dipolar ion which means it carries both positve and negative charges
Whats an isolecteric point
PH at which amino acid carries equal positive or negative charge
Sulphur group amino acids
Methionine and cysteine
Hydroxyl group amino acids
Serine threonine and tryosine
Imino group
Proline
Branched chain
Valine leucine and isoleucine
Name some clinical implactions of amino acids
▪️Some amino acids are precursors to imp compounds as hormones ex GABA receptor and melanin and def can cause serious health problems
▪️some amino acids have been linked to obesity such as sulphur containing a.a(methanine and cytesine)
▪️intake of branched chain a.a(valine,leucine and isoleucine) is useful for patients suffering from liver disease
▪️intake of excessive over the counter a.a for the gym can cause kidney failure
▪️defects in globin in Hb can cause heamolysis or inability of O2 delivery to tissues
▪️def of immunoglobins causes infections
▪️def of cogulation factors leads to uncontrollable wound bleeding
Name covalent bonds
Peptide and disulfide
Name non covalent bonds
Ionic and Hydrogen and electrostatic forces
Whats the biomedical imp of H bonds
Plays a role in prt folding
Form 2 bonds between Andenine and thymine
Form 3 bonds between guanine and cytosine
