L24-The Immune system in early life Flashcards
Which immune system predominates throughout early life?
The Innate immune system
What attempts to protect the foetus from infections in the mother?
The placenta acts as a barrier but is not perfect.
What are the effects of congenital rubella on a baby?
Sensorineural deafness
Eye disease
Congenital heart disease
When is maternal IgG transferred to the foetus?
In the last trimester of pregnancy
What is the downside of placental IgG transfer?
The transmission of IgG mediated autoimmune disease from the mother to the child.
How does breast feeding protect the baby against infections?
It contains high quantities of secretory IgA which protects the babies digestive systems.
What types of vaccines are used to help immunise infants?
Conjugate vaccines are used to help overcome the immaturity of the immune system.