L24: Ectoparasitic Infections+RMSF Flashcards

1
Q

most serious of the mites

A

sarcoptes scabiei

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2
Q

Scarcoptes scabiei aka

A

Scabies
Mange
Crusted scabies
Seven year itch

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3
Q

Small mite with short legs

A

sarcoptes scabiei

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4
Q

Where is the female scabies mite fertilized?

A

Skin surface

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5
Q

Female scabies mite life cycle

A

once fertilized, burrows into epidermis

lives 5 weeks, die in burrow where it has laid eggs

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6
Q

Male scabies mite life cycle

A

shorter life span, remains on skin surface/produces shallow burrow

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7
Q

Scabies eggs

A

laid under skin
4 days incubation: larva emerges
2 weeks after hatching: adult mite

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8
Q

main clinical manifestation of scabies

A

pruritis

worse at night

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9
Q

first time someone is infected with s scabiei

A

sensitization and allergic response takes weeks to develop

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10
Q

s scabiei reinfections

A

already sensitized so pruritis can develop within 24 hours

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11
Q

Crusted/Norwegian scabies

A

HIV patients
incubation 1 month
crusted lesions teeming with mites. v v itchy

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12
Q

How is scabies transmitted?

A

person to person
can be an STI
zoonotic
crowded living conditions

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13
Q

How to identify scabies

A

mineral oil + scrape lesions + microscope

look for mite, mite parts, eggs, fecal pellets

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14
Q

Pubic lice/crabs aka

A

Phthirus pubis

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15
Q

Decribe phthirus pubis

A

Bigger mites with longer legs and “clamps”

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16
Q

How do pubic lice lay their eggs?

A

nits cemented to hair

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17
Q

Identify a pubic lice infection

A

visualize a louse or nit

18
Q

Head louse

A

Peiculus capitis

19
Q

Body louse

A

P humanus corporus

20
Q

what do head/body lice carry?

A

epidemic typhus

21
Q

Egg-to-egg cycle of a louse

A

Nit cemented to hair or clothing fibers

cycle takes 3 weeks

22
Q

Vagabond’s disease

A

years of lice infestation causes darkened, thickened skin

23
Q

Human flea aka

A

Pulex irritans

24
Q

Pulex irritans description

A

1-4 mm in length

short spikes on legs for attachment

25
Q

Pulex irritans are considered

A

parasites, absolutely need blood to survive

26
Q

what causes an allergic reaction/rash from a flea?

A

during a blood meal, they inject saliva

has at least 15 substances that initiate allergic responses

27
Q

Scabies vs fleas: rash

A

Scabies: tunnel or burrow beneath skin
Fleas: linear pattern, groups of 3/4 bites

28
Q

Scabies vs fleas: where do they live?

A

Scabies: on human skin, lay eggs beneath it
Fleas: do not live on humans, prefer pets

29
Q

Scabies vs fleas: spread

A

Scabies: skin-to-skin, sexual, family members
Fleas: not contagious

30
Q

Scabies vs fleas: mobility

A

Scabies: crawl very slowly
Fleas: jump long distances

31
Q

Ticks that’ll give you rocky mountain spotted fever (3)

A

American dog tick
Rocky mountain wood tick
Brown dog tick AZ

32
Q

Causative agent of Rocky mountain spotted fever

A

Rickettsia Rickettsii

33
Q

Rickettsia morphology

A

G-
Obligate intracellular
Non motile
Pleomorphic (cocci, rods, threadlike)

34
Q

Brown dog tick seasonality

A

April-October

peak in June and july

35
Q

When do Rocky Mountain Spotted Fever symptoms first appear?

A

2-14 days after tick bite

36
Q

How does Rocky Mountain Spotted Fever present once symptomatic?

A

Sudden onset of fever and headache

non-specific: N/V, abdominal pain, anorexia, conjunctivitis

37
Q

Rickettsia life cycle

A

invade endothelial cells that line blood vessels
causes rashes
fatal

38
Q

2 types of Rocky Mountain Spotted Fever rashes

A
  1. Small, flat pink non itchy macules
  2. Red to purple spotted petechial rash
    - pinpoint hemorrhages (60%)
    - 6 days post infection
    - sign of late disease and severe infection
39
Q

Diagnosis and treatment of Rocky Mountain Spotted Fever

A

Not easy, tests aren’t great, Abs take 7-10 days postinfection
DON’T delay treatment

40
Q

Gold standard for detection of Rocky Mountain Spotted Fever

A

Indirect Immunofluorescense of Rickettsia antigen

2 samples 2-4 weeks apart