L2: intrathoracic malignancy Flashcards

1
Q

two primary intrathoracic malignancys

A

lung

pleura

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2
Q

lung malignancy=

A

carcinoma (>90%)

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3
Q

pleura malignancy=

A

malignant mesothelioma

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4
Q

90% of cases of lung cancer caused by

A

smoking

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5
Q

relative risk of passive smoking

A

1.25

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6
Q

3 other causes of lung cancer

A

radon
asbestos
chromates

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7
Q

where does radon naturally occur

A

soil and rocks

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8
Q

highest rates of radon in the UK

A

cornwall

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9
Q

3 occupations with increased risk of radon

A

aircrew
nuclear fuel plant
power station workers

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10
Q

3 properties of a maligant neoplasm

A

excessive growth
local invasiveness
ability to metastasise

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11
Q

3 indirect actions of carcinogens

A

induction of chronic inflammation
hyperplasia
metaplasia

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12
Q

what are mutations called that are essential for tumour cell survival

A

driver mutations

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13
Q

how many carcinogens in cigarette smoke

A

43

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