L19 - Tumour Classification Flashcards

1
Q

Name 2 types of benign epithelial tumour

A
  • papilloma (SURFACE EPITHELIUM)

- adenoma (GLANDULAR EPITHELIUM)

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2
Q

What is the name of a benign tumour of squamous epithelium e.g. skin?

A

Squamous cell papilloma

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3
Q

What is the name of a benign tumour of the ductal epithelium of the pancreas?

A

Pancreatic cystadenoma

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4
Q

What are the exceptions to the normal rules of naming benign epithelial tumours?

A
  • melanoma
  • lymphoma
  • seminoma
  • mesothelioma
    etc
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5
Q

What are malignant epithelial tumours called?

A

Carcinomas

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6
Q

How are malignant epithelial tumours derived from surface epithelial named?

A

By prefixing carcinoma with the cell of origin eg. squamous cell carcinoma

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7
Q

What is the name for malignant tumours derived from glandular/ductular epithelium?

A

Adenocarcinomas

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8
Q

Name a benign tumour of stratified squamous epithelium eg. skin, oropharynx etc.

A

Squamous cell papilloma

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9
Q

Name a bening tumour of basal cells of the skin

A

Basal cell papilloma

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10
Q

Name a benign tumour of transitional epithelium of the bladder

A

Transitional cell papilloma

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11
Q

Name a benign tumour of glandular epithelium of liver

A

Liver cell adenoma

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12
Q

Name a benign tumour of glandular epithelium of thyroid

A

Follicular adenoma

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13
Q

Name a malignant tumour of basal cells of the skin

A

Basal cell carcinoma

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14
Q

Name a malignant tumour of glandular epithelium of colon

A

Colonic adenocarcinoma

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15
Q

Name a malignant tumour of glandular epithelium of breast

A

Breast adenocarcinoma

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16
Q

what is the rule for classifying benign mesenchymal tumours?

A

Prefix = tissue or cell of origin

Suffix = ‘-oma’

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17
Q

What is a benign tumour of bone?

A

Osteoma

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18
Q

What is a benign tumour of adipose tissue?

A

Lipoma

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19
Q

What is a benign tumour of smooth muscle?

A

Leiomyoma

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20
Q

What is a benign tumour of skeletal muscle?

A

Rhabdomyoma

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21
Q

What is a benign tumour of a blood vessel?

A

Angioma / haemangioma

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22
Q

What is a benign tumour of cartilage?

A

Chondroma

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23
Q

What is a benign tumour of fibrous tissue?

24
Q

What are malignant mesenchymal tumours called?

25
How are malignant mesenchymal tumours named?
Prefix = tissue or cell of origin Suffix = '-sarcoma'
26
What is a malignant tumour of adipose tissue?
Liposarcoma
27
What is a malignant tumour of smooth muscle?
Leiomyosarcoma
28
What is a malignant tumour of cartilage?
Chondrosarcoma
29
What is a benign tumour of melanoyctes called?
Melanocytic nevus
30
What is a malignant tumour of melanocytes called?
Melanoma
31
Name 3 types of malignant tumour of blood cells
- leukaemia - lymphoma - myeloma
32
Name 5 types of CNS tumours
- meningioma - astrocytoma - oligoendroglioma - ependymoma - medulloblastoma
33
What is a meningioma?
Arises from meningeal tissue of brain (usually benign)
34
What is an astrocytoma?
Arise from the star-shaped glial cells called astrocytes
35
Name a type of astrocytoma
Glioblastoma multiforme (most common and most malignant of the glial tumours)
36
What is an oligoendroglioma?
Originate from the oligodendrocytes of the brain or from a glial precursor cell
37
What is an ependymoma?
Arises from the ependyma, a tissue of the central nervous system
38
Where are germ cell tumours common?
Gonads
39
How can germ cell tumours be divided?
- seminomatous | - non-seminomatous
40
Give an example of a seminomatous germ cell tumour
Seminoma
41
Give an example of a non-seminomatous germ cell tumours
Teratoma (teeth/hair/muscle/neural/cartilage)
42
What are the features of embryonal tumours?
- occur in very young (under 5) | - have a histological resemblance to embryonic cells of that organ
43
Give 4 examples of embryonal tumours
- retinoblastoma (in eye) - nephroblastoma (Wilm's tumour of kidney) - neuroblastoma (adrenal medulla or nerve ganglia) - hepatoblastoma (liver)
44
What is a carcinosarcoma?
Malignant tumors that consist of a mixture of carcinoma (or epithelial cancer) and sarcoma (or mesenchymal/connective tissue cancer) eg. in ovaries
45
Name 4 malignant tumours with benign names
- melanoma - mesothelioma - myeloma - lymphoma
46
What is a hamartoma?
- non-neoplastic overgrowth of normal tissue - indigenous to the site of occurrence - developmental abnormalities - eg. lung hamartoma
47
Hamartomas usually consist of what?
2 mature cell types normally found in the organ in which the lesion lies e.g. lung hamartoma = cartilage and bronchial epithelium
48
What is a choristoma?
- excess of normal tissue in an abnormal situation - nodules of organ parenchyma in another organ - aka. heterotropic rests - eg. normal (non-neoplastic) pancreas nodule in stomach
49
what is a primary tumour?
tumour has arisen in organ of mutation
50
what is a secondary tumour?
tumour has escaped original environment via lymphatic/vascular system setting up another metastatic deposit in the body
51
what is the name of a benign tumour of surface (non-glandular / non-secretory) epithelium?
papilloma
52
what is the name of a Benign tumour of glandular / secretory epithelium?
ADENOMA
53
what is the suffix for a benign epithelial tumour?
-oma
54
what is the rule for classifying benign epithelial tumours?
CELL TYPE of origin (eg squamous/colonic) → surface/glandular (Papill-/aden-) → suffix: -oma
55
what is the rule for classifying malignant epithelial tumours?
Named by prefixing ‘carcinoma’ with epithelial cell of origin e.g. BASAL CELL CARCINOMA
56
what is the rule for classifying malignant epithelial tumours of secretory epithelium?
Named by prefixing ‘adenocarcinoma’ with epithelial cell of origin