L13 Cerebellum Flashcards

1
Q

Cerebellum help in

A

1- timing of motor activities
2- rapid smooth progression from one muscle movement to the next.
3- It also helps to control intensity of muscle contraction when the muscle load changes
4- controlling necessary instantaneous interplay between agonist and antagonist muscle groups.

So Coordinate voluntary movement
Nonverbal learning and memory
And its Called: silent area of the brain.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The cerebellum is especially vital
during:

A

rapid muscular activities
such as;
- running,
- typing,
- playing the piano,
- talking.
—

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Loss of cerebellum can cause

A

total incoordination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Part of cerebellum controlling equilibrium

A

vestibular system

flocculonodular
فيه اسم ثاني ورا

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Functional division of cerebellum

A

1- vestibulocerecellum ( flocculonodular)
2- spinocerebeelum ( vermis , intermediate zone )
3-Cerebrocerebellum ( lateral zone )

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Vestibulocerebellum

A

Input:
Vestibular nuclei

Function:
Regulate and balance eye and posture movement ,equilibrium

Damage:
Inability to stand upright
Cerebellar nystagmus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Spinocerebellum

A

Input :
Spinal cord

Function:
-Lateral portion (هو نفسه له جزأين يعني غير اللترال الاساسيه )
Mov. Of distal muscle ( gross mov. during walking )

-vermis
Movement of proximal muscles

Damage:
Overshoot ( tension tremors )
Impaired gait

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cerebrocerebellum

A

Input :
Cerebral cortex ( relayed in pons )

Function:
Planning and timing of sequential movements
speech

Damage :
Ataxia
Incoordination Of complex porpusful mov.
Failure of smooth progression of movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

representations of the different parts of the
body in cerebellum is seen in

A

vermis and intermediate zones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The axial portions of the body represented in
lie in the ………………………….. of the cerebellum,
whereas The limbs and facial regions lie in the ………………..

A

vermis

intermediate zones.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

large……………………of cerebellar hemispheres do not have topographical representations of the body.

A

lateral portions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

These areas of the cerebellum receive their input signals almost exclusively from the cerebral cortex, especially from:

  • premotor areas of the frontal cortex and
  • somatosensory and other sensory association areas of the
    parietal cortex.
A

lateral part of cerebellum

((play important roles in planning and coordinating the body’s rapid sequential muscular activities that occur one after another within fractions of a second))

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Afferent Pathways from other parts of the brain to cerebellum:

A
  1. Corticopontocerebellar pathway
  2. Olivocerebellar tract
  3. Vestibulocerebellar fibers
  4. Reticulocerebellar fibers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Afferent pathways from the periphery
To cerebellum

A

1- The dorsal spinocerebellar tract —
2- The ventral tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

signals transmitted in the dorsal spinocerebellar tracts come mainly from:

A
  • the muscle spindles
  • and to a lesser extent from other somatic receptors throughout the body, such as:
    Golgi tendon organs,
    —
    large tactile receptors of the skin,
    —*joint receptors.

—All these signals apprise the cerebellum of the momentary status of:
(1) muscle contraction
(2) degree of tension on the muscle tendons,
(3) forces acting on the surfaces of the body
(4) positions and rates of movement of the parts of the body,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The ventral spinocerebellar tracts receive less information from the
peripheral receptors. —
Instead, they are excited mainly by:

A

motor signals arriving in the anterior horns of the spinal cord from the
brain through:

— (1) the corticospinal & rubrospinal tracts
(2) the internal motor pattern generators in the cord itself.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

ventral fiber pathway tells the cerebellum which motor signals
have arrived at the anterior horns; this feedback is called the

A

efference copy of the anterior horn motor drive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

the most rapid conduction
in the central nervous system.

A

spinocerebellar pathways can

120 m/sec

19
Q

All the deep cerebellar nuclei
receive signals from two sources:

A

(1) the cerebellar cortex
(2) the deep sensory afferent tracts to the cerebellum.

20
Q

input signal arrives in the cerebellum, it divides and goes
in two directions:

A

(1) directly to one of the cerebellar deep nuclei and
(2) to a corresponding area of the cerebellar cortex overlying the
deep nucleus.

21
Q

all input signals that enter the
cerebellum eventually end in the deep nuclei in the form of

A

—-initial excitatory signals —
-followed a fraction of a second later by inhibitory signals.

22
Q

general plan of the major efferent pathways

A
  1. A pathway that originates in the midline of the cerebellum (the vermis))
    — ((association with the equilibrium apparatus and brain stem vestibular nuclei to control equilibrium))
  2. A pathway that originates in the intermediate zone of the cerebellar hemisphere
    —((helps to coordinate mainly the reciprocal contractions of agonist and antagonist muscles
    in the peripheral portions of the limbs))
  3. A pathway that begins in the cerebellar cortex of the lateral zone of the cerebellar hemisphere
    ((helping coordinate sequential motor activities initiated by the cerebral cortex))
23
Q

The climbing fibers originate from the

A

inferior olives of the
medulla.

24
Q

action potential in climbing fiber of of cerebellum is called

A

complex spike.

25
Q

mossy fiber input to the Purkinje cell type of its action potential?

(multiple sources: from the higher brain, brain stem, and spinal cord ) طالع من

A

simple spike

26
Q

Direct stimulation of the deep nuclear cells by both the climbing and the mossy

A

fibers excites them

By contrast, signals arriving from the Purkinje cells ((inhibit them))**

27
Q

Importance of damping in cerebellum

A

stop the muscle movement from overshooting

اول شيء تحفيز سريع بعدها فيدباك يثبط العملية لان cerebellum بطبيعته favor excitation

28
Q

Inhibitory cells of cerebellum

A

Purkinje cells,
basket cells
stellate cells.

29
Q

typical function of the cerebellum is to help provide

A

rapid turn-on signals for the agonist muscles and simultaneous reciprocal
turn- off signals for the antagonist muscles at the onset of a movement.

—Then on approaching termination of the movement, the cerebellum is mainly responsible for timing and executing the turn-off signals to the agonists and turn-on signals to the antagonists.

30
Q

Cerebellar disorders

A

Dysdiadochkinesia
Ataxia
Nystagmus
Intention tremor
Slurred speech
Hypotonia

31
Q

Archicerebellum function

A

Body equilibrium
Eye movement

32
Q

Paleocerebellum function

A

Muscle tone
Gait

33
Q

Neocerebellum function

A

Planning and initiation of movement
Regulate fine limb movement

34
Q

Limbic Ataxia —
— Hypotonia
— Dysarthria
Dysdiadochokinesia
— Intention Tremor

Damage to

A

Neocerebellum

35
Q

Truncal & Gait ataxia
Damage to

A

Paleocerebellum

36
Q

Nystagmus and gait dysfunction damage to

A

Archicerebellum

37
Q

Two of the most important symptoms of cerebellar disease are

A

dysmetria and ataxia .

38
Q

lesions in the spinocerebellar
tracts led to

A

Dysmetria and ataxia

39
Q

Past pointing means

A

moves the hand or some other moving part of the body
beyond the point of intention.

past pointing is actually a manifestation of dysmetria

40
Q

Hypotonia Due to

A

Loss of the deep cerebellar nuclei, particularly of the
dentate and interposed nuclei,

loss of cerebellar facilitation

41
Q

Dysarthria (failure of progression)

A

§ some syllables loud,
§ some weak,
§ some held for long intervals,
§ some held for short intervals,

42
Q

Failure of progression - Dysdiadochokinesia

A

fails to predict where the different parts of the body will be at a given time,

jumbled movements
may begin much too early or much too late,

43
Q

oscillate with first overshooting the
mark and then vibrating

A

intention tremor or an action tremor,

and it results from cerebellar overshooting
and failure of the cerebellar system to “damp” the motor movements.

44
Q

tremor of the eyeballs that occurs usually when one
attempts to fixate the eyes on a scene to one side of the head;

A

Cerebellar nystagmus

failure of damping flocculonodular lobes of th cerebellum are damaged