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microbiology > L10. mycobacteria > Flashcards

L10. mycobacteria Flashcards

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Biology 101 flashcards
1
Q

…

A

…

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2
Q

what is the target cell to infect for mycobacteria?

A

in alveolar macrophages

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3
Q

what is the moa of mycobacteria?

A

teh response to mycobacteria by immune system causes the disease

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4
Q

how do we refer to mycobacteria that does NOT cause TB?

A

Atypical mycobacteria/ MOTT…

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5
Q

how doe we refer to mycobacteria that cause leprosy??

A

xx

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6
Q

what is the most common infection caused by mycobacteria?

A

TB

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7
Q

what is the second most caused infection by mycobacteria>

A

leprosy..

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8
Q

what are the four groups of NT - MOTT? (runyon classification)

A

1.slow growing …
2.
3.
4.

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9
Q

what is the prevalence of mycobacteria infection?

A

one third of the population

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10
Q

….

A

….

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11
Q

what is the difference b/w infection and disease?

A

infection - not necessarily disease

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12
Q

how is TB transmitted?

A

aerosol transmission: after sneezing the mycobacteria stay in “clouds” of air

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13
Q

droplet vs aerosol transmission

A

droplet -

aerosol -

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14
Q

what is the pathogenesis of pulmonary TB?

A

intracellular multiplication - alveolar …macrophages

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15
Q

what is caseation?

A

cheese in lungs…

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16
Q

what is the most common cause of addisons diseaase?

A

x

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17
Q

what is pott’s disease?

A

x

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18
Q

what is skin TB?

A

lupus….

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19
Q

x

A

IL 12 tnf alpha inf gammma

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20
Q

3 characteristics of tb??

A

langhans giant cells, caseous granulomas, epthilod…???

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21
Q

primary infection of tb called?

A

ghons focus

22
Q

does ghons focus mean disease?

A

no?

23
Q

x

A

night sweats, …

24
Q

what are the x

A

tuberculin skin test and ifn gamma - exposre tessts

25
Q

what are the disease Tb tests?

A

micrscopy and culture

26
Q

What is tuberculin (PPD) skin test - TST

A

x

27
Q

what is induration?

A

hard swelling

28
Q

what is IGRA?

A

interferon gamma release assay

29
Q

what are the antigens used for igra? (2)

A

esat - 6, cfp - 10

30
Q

TST vs IGRA? (3)

A

x

31
Q

what is a common urine contaminant during urine test (usually in men)?

A

mycobactera smegmatis…

32
Q

what is auramine stain>?

A

x

33
Q

what is cord factor?

A

mark of virulent mTB

34
Q

skip lab diagnosis

A

x

35
Q

what media is required to grow TB?

A

L -J media

36
Q

whatis the apperance of TB on l - j media?

A

rought tough…

37
Q

…

A

….

38
Q

what are the challeneges of treatment (apart from non compliace?) (2)

A

x mdr …

39
Q

what are the four drugs of TB?

A

isonia…

40
Q

pan susceptible

A

tb is suceptible to all four drugs…

41
Q

group A b C drugs?

A

x

42
Q

…

A

….

43
Q

what is DOT?

A

directly observed therapy - WHOs strategy to eradicate TB

44
Q

…

A

….

45
Q

what is leprosy?

A

…

46
Q

…

A

…

47
Q

what are the two different types of leprosys? (2)

A

x

48
Q

can you culture m. leprae?

A

no

49
Q

what is z - n smear?

A

…

50
Q

what is leonine facies

A

x

51
Q

m. avium and intercellular..

A

x

52
Q

what is MAC? what are the diesease caused ? (3)

A

x

microbiology (8 decks)

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