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microbiology > L1 Fungi > Flashcards

L1 Fungi Flashcards

1
Q

hyphae

A

x

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2
Q

mycelium

A

x

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3
Q

rigid cell wall composition

A

x

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4
Q

fungi cell membrane component

A

x

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5
Q

chitin

A

structural part

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6
Q

beta 1,3 glucan

A

sticking out

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7
Q

amphotericin B

A

x

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8
Q

Nystatin

A

x

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9
Q

fungi environment requirement

A

x

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10
Q

yeast reproduction method

A

budding

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11
Q

pseudohyphae

A

long chains of cells…

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12
Q

Yeast vs bacteria growth time

A

take longer

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13
Q

Dimorphic fungi

A

37 deg - yeast, cold environment - mold

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14
Q

“yeast in the ____, mold in the ____”

A

beast, cold

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15
Q

Longitudinal extensions and produce spores

A

molds

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16
Q

what proportion of fungi are linked to disease

A

300 vs 100,000 species

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17
Q

mycoses

A

?

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18
Q

labaratory diagnoses methods for fungi

A

x

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19
Q

thermal dimorphism

A

37 deg - yeasts

25 - 30 deg - molds

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20
Q

Fungi method of transmission/entry

A

spores - inhaled!

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21
Q

Candida

A

ntibiotic therapy, catheters -> immunosuppressed conditons

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22
Q

asperigillus

A

x

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23
Q

main virulence factor

A

thermal dimorphism

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24
Q

Most fungal treatments are _____

A

topical

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25
Q

KOH mount

A

kills keratins and other cells to see only fungi in the plate

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26
Q

PAS stain

A

x

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27
Q

flucytosine

A

analogues nucleic acid…

28
Q

azoles

29
Q

Acid fast vs partial acid fast

30
Q

gluco….. and galato….

A

Antigen detection test

31
Q

other modes of fungal transmission

32
Q

organ most infected by fungi

33
Q

conidia

A

another name for fungal spore

34
Q

are fungi transmitted person to person?

A

nope, relax

35
Q

TB vs fungal infection

A

similar symptoms, normally will mention it is fungi

36
Q

clinical presentation of fungi

A

asymptomatic: x
calcified granulomas
…

37
Q

culture for fungi

38
Q

characterisitc of blastomyces

A

thick cell wall!

39
Q

blasto.. usually located in

A

forest, decaying wood - no animals!
ohio, river valley
canada

40
Q

blasto.. uually infects

41
Q

morphology of bastomyces

A

round yeast cells, budding

42
Q

cutaneous blato.. found in

A

people in contact w/ sil…

43
Q

immune system is adapted to do what to fungi?

A

inhibit transformation from mold to yeast

44
Q

whats special about the yeast form of fungi?

A

very resistant to killing - thick capsule

45
Q

the presenc eof yeats form indictes what in humans?

46
Q

pyrogranulmatous lesions

47
Q

calcofluor

48
Q

size of spore?

A

1 to 2 micrometer

49
Q

location of histoplasma

A

chicken coups, associated with bird and bat droppings… nitrogen rich soil!
ohio river valley and mississipi

50
Q

histoplasma infection aka

A

ohio valley fever

51
Q

hisotplasma grows where?

A

intacellularly in macrophages

52
Q

histo.. important virulance factor?

A

mediate pH within phagolysosome

53
Q

histo.. staining

54
Q

Cocci… location

A

alkaline soil

semiarid hot climates - arizona

55
Q

cocci… structure

A

spherule form containing endospores

56
Q

arthroconidia

A

specific for cocci… in natural form

57
Q

cocci… structure in body

A

spherules (little yeast cell with endospores inside it)

58
Q

two forms of cocci…

A

soil - artoconidia

beast - spherules w/ endospores inside them

59
Q

disease characteristic of cocci..

60
Q

test for cocci..

A

immunodiffusion test

61
Q

4 antifungals and function

62
Q

issue with taking antifungals orally

A

nephrotoxic

63
Q

often give ampho B w/ _______

A

flucytosine

64
Q

what do azoles inhibt?

65
Q

wht does c14 demethylase do?

66
Q

what does grisofulvin do and where does it inhibit fungi?

A

interfere w/ spindle formation - inhibit cell division

x

67
Q

where doe terbinafine act?

microbiology (8 decks)

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