L 32 Asthma & COPD Flashcards by Mac Mac | Brainscape

Q

What do Rescue Meds do?

A

short acting tx symptoms AFTER they have started

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Q

What do Controller Meds do?

A

long acting PREVENT symptoms before they start

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Q

Short-acting Beta Agonist MOA?

A

Inc. cAMP = SM relax

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Q

Short-acting Beta Agonist SE?

A

tremor

tachycardia

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Q

Long-acting Beta Agonist MOA?

A

Inc. cAMP = SM relax

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Q

Long-acting Beta Agonist contraindications?

A

single agent in asthma

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Q

Anticholinergics MOA?

A

(-) M3 receptors on SM

= (-) bronchoconstriction

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Q

Anticholinergics contraindications?

A

glaucoma

prostate hypertrophy

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Q

Corticosterioids MOA?

A

alter gene transcription

= less infl.

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Q

Corticosteroids SE?

A

pneumonia
osteoporosis

oral thrush – rinse after use
cataracts

voice change

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Q

Combine Long-acting Beta Agonist with?

A

corticosteroids

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Q

Leukotriene inhibitor MOA?

A

(-) LTE receptors

or

(-) leukotriene synthesis

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Q

Methylxanthines MOA?

A

(-) PDE
(-) Adenosine

activate histone deacetylase

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Q

Anti- IgE MOA?

A

(-) IgE from pro inflammatory signaling

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Q

Anti-IgE indications?

A

moderate - severe asthma

high IgE

allergies

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Q

Anti- IL5 MOA?

A

IL-5 receptor antagonist

- eosinophil production

Q

Anti- IL5 Indications?

A

moderate - severe asthma

high eosinophil count

Q

What are the cornerstone of therapy for asthma?

A

inhaled corticosteroids

Q

What is the 1st line therapy for COPD?

A

LABA

or

Anticholinergic

Q

What are COPD medications?

A

Beta Agonists
Anti Cholinergic

Inhaled Corticosteroids
Theophylline

PDE4 (-)

Q

PDE4 (-) MOA?

A

Inc. cAMP = anti infl. effects

Q

PDE4 (-) SE?

A

GI upset
Diarrhea
Wt. Loss

Q

What treats severe COPD?

A

inhaled corticosteroids

Q

What are controller meds for COPD?

A

LABA / LAMA combo

Q

Beta Agonist drugs?

A

-erol

Q

Anticholinergic drugs?

A

-ium

Q

Corticosteroid drugs?

A

-sone

Q

What needs to be monitored for a pt on Theophylline?

A

blood levels