krebs cycle Flashcards
where krebs occurs
mitochondrial matrix
krebs: aerobic/anaerobic
aerobic
how many times does krebs happen
twice
krebs net products
2 ATP, 6 NADH, 2 FADH
carbons start and end in Krebs
2x acetyl-CoA, ends w 3 1C CO2s for EACH 3C PYRUVATE
electron carriers in krebs cycle
2x [ 3NAD + 1FAD => 3NADH + 1FADH]
Krebs: step 1
acetyl + oxaloacetate = citrate (CONDENSATION)
Krebs: step 2
citrate => isocitrate (ISOMERIZATION)
Krebs: step 3
isocitrate => a-ketoglutarate (NADH, CO2) (1ST OXIDATION + DECARBOXYLATION)
Krebs: step 4
a-keto => succinyl-CoA (NADH, CO2) (2ND OXIDATION + DECARBOXYLATION)
Krebs: step 5
succinyl CoA => succinate (ATP by sub.phosph.) (SUB LEVEL PHOSPH)
Krebs: step 6
succinate => fumarate (FADH2) (3RD OXIDATION)
Krebs: step 7
fumarate => malate (CONVERSION + H2O)
Krebs: water
released in step 7
Krebs: step 8
malate => oxaloacetate (NADH) (4TH OXIDATION + REGENERATION OF OXA.)