chapter 2 pt 3 Flashcards
active transport:
transport across membrane AGAINST or UP concentration gradients
active transport requires the
expenditure of energy
main source of energy in the cell:
adenosine triphosphate/ATP
atp is derived from an
adenosine nucleotide but with a TRIPLE PHOSPHATE GROUP instead of a single => hydrolysis at the end of phosphate group releases energy
ATP undergoes hydrolysis and loses
terminal phosphate group = forms ADP and inorganic phosphate
ATP vs ADP
triphosphate vs diphosphate
transport proteins in active transport are
carrier proteins rather than channel proteins
ion pumps: carrier proteins using ATP to
pump ions across membrane against conc gradient
example of ion pumps
Na-K pump: exchanges sodium for potassium
ATP powers the changes in protein shape (conformation) by
phosphorylating the carrier protein (transfers phosphate group to protein)
animal cell has a much higher concentration of K and much
lower concentration of sodium compared to surroundings: cell membrane maintains steep gradient by ion pumping Na out and K in
primary vs secondary active transport
primary uses ATP, secondary uses ELECTROCHEMICAL GRADIENT
secondary active transport:
electrochemical gradient created by primary active transport via ION PUMP is used by a DIFFERENT PROTEIN to transport other molec.s
secondary active transport is common in
bacteria and plant cells
active transport: cells may need to move molecules
AGAINST conc gradient
- shape change in carrier protein transports solute from one side of membrane to another
- protein pump
- costs energy = ATP
passive transport summary:
simple diffusion, osmosis, facilitated diffusion
passive transport summary: SIMPLE DIFFUSION
diffusion of nonpolar, Hphobic molecs/small molecs
- lipids, O2, CO2
- high to low conc
passive transport summary: OSMOSIS
diffusion of water molecs
- high to low conc gradient
passive transport summary: FACILITATED DIFFUSION
diffusion of polar, Hphilic molecs
- thru channel/carrier proteins
- high to low concentration gradient
active transport summary:
movement AGAINST conc gradient
- low to high conc. gradient
- protein pump/carrier protein
- requries ATP
membrane assisted transport:
method for macromolecules that are TOO BIG to cross membrane thru channel/carrier protein
membrane assisted transport: cell forms
vesicles to surround incoming material
- requires energy from cell
- two types: ENDOcytosis and EXOcytosis
membrane assisted transport: ENDOcytosis
cell membrane engulfs extracellular material to bring inside cell, pinches off to form vesicle inside cell
- phagocytosis
- pinocytosis
- receptor-mediated
membrane assisted transport: endocytosis: PHAGOCYTOSIS
endocytosis involving SOLID particles: cell-eating