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IHO Week 2 > Krafts Transfusion medicine > Flashcards

Krafts Transfusion medicine Flashcards

1
Q

What determines blood group?

A

Antigens on RBC surface

A, B, both A and B, or none (O)

also Rh

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2
Q

A person with type A blood has antibodies against:

A

Type B

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3
Q

Universal acceptor?

A

AB

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4
Q

Universal donor?

A

O

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5
Q

Rh factor refers to the ___ antigen.

A

D

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6
Q

What are the 6 blood products?

A

whole blood

Red cells

platelets

granulocytes

cryoprecipitate

fresh frozen plasma

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7
Q

Indications for Whole blood transfusion?

A

massive hemorrhage

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8
Q

Indications for RBC tranfusion?

A

low Hgb

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9
Q

Indication for leukocyte reduced red cells?

A

they decrease the risk of alloimmunization and allergic reaction

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10
Q

Indications for frozen RBCs?

A

rare blood types

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11
Q

Indications for granulocyte transfusion?

A

sepsis in neutropenic patients

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12
Q

Indication for platelets?

A

bleeding due to thrombocytopenia

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13
Q

Indication for FFP?

A

bleeding due to multiple factor deficiencies

**includes all coag factors

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14
Q

Indications for cryoprecipitate?

A

low fibrinogen, vW diseas, hemophilia A, XIII deficiency

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15
Q

Factor VIII indication:

A

hemophilia A

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16
Q

Factor IX indication:

A

hemophilia B

17
Q

Indication for albumin?

A

hypovolemia

hypoproteinemia

18
Q

Indication for IvIG?

A

disease prophylaxis, autoimmune disease, immune deficient states

19
Q

Blood test adding antibodies to patient’s blood?

A

Forward type

20
Q

Blood test adding patients serum to known cell typed blood?

A

Reverse type

21
Q

With blood testing how do you know if a test is positive after adding AHG (anti-human globulin)?

A

agglutination

22
Q

Symptoms of acute hemolytic transfusion reaction:

A

fever

chest pain

hypotension

23
Q

What causes delayed hemolytic transfusion reactions?

A

patient has antibodies to non-ABO antigens

**no cytokine storm

Presentation: falling Hgb after transfusion

24
Q

What is the first thing to do if you suspect an acute transfusion reaction?

A

STOP THE TRANSFUSION

25
Q

How do you treat iron overload?

A

give iron-chelating agents

**patients with chronic anemias are at greatest risk

26
Q

When donor lymphocytes attack host?

A

Graft vs. Host disease

27
Q

Infection risk from highest risk to lowest:

A

Bacterial 1 in 50,000-500,000

Hep B 1 in 300,000

Hep C 1 in 2 million

HIV 1 in 2 million

IHO Week 2 (12 decks)

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