Benign Leukocytosis Flashcards
Causes of mature neutrophilia?
infection
inflammation
stress
hormones
Only time toxic changes are seen in neutrophils?
Infection
What does toxic changes in a neutrophil look like?
Increased granules
Little blue dot in neut?
Dohle bodies
Cytoplasm vacuolization = ?
BAD infx
Causes of immature neutrphilia?
infection
inflammation
severe anemia
something filling up marrow
Left shift = ?
more bands and metamyelocytes
Leukoerythroblastotic reaction = ?
left shift + nucleated RBCs
Normal lymphocyte immunophenotype in blood:
T-cells 80%
B-cells 15%
NK cells 5%
Lots of funny looking lymphocytes = ?
Reactive lymphocytosis
Causes of mature lymphocytosis?
infectious lymphocytosis
Bordetella pertussis
Transient stress
Biggest cause of reactive lymphocytosis?
Infectious mono
How do you differentiate between left shift and CML?
LS has no basophilia and fewer immature cells
Defining dx for CLL?
age over 40
Basophilia–lots of basophils, think?
CML!