KQ4 - ADVANCES IN MEDICAL KNOWLEDGE Flashcards

1
Q

THE FOUR HUMOURS ?

A

The four humours came from the ideas of Hippocrates
The body has four important liquids and if they became out of balance a person would become unwell.
Blood, yellow bile, black bile, phlegm - Air, fire, earth, water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

GALEN ?

A

AD 129 furthered Hippocrates work by creating the idea of opposites, hot too balance cold etc.
His work in dissecting pigs discovered the nervous system
He discovered that the brain controls speech and that the arteries carry blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

ASTROLOGY ?

A

Medieval physicians believed that the movement of the planets affected people’s health
They consulted a book called a Valemecum, which contained the zodiac signs and zodiac man chart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

THE CHURCH’S INFLUENCE ?

A

The Church had considerable sway over medical ideas
They funded universities throughout Europe
They supported the ideas of Hippocrates and Galen
Church thought disease was a punishment from God and that atonement through processions and self-flagellation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

THREE EARLY MODERN FIGURES ?

A

Andreas Vesalius
Ambroise Pare
William Harvey

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

WORK OF VESALIUS ?

A

Andreas Vesalius was a professor of anatomy at Padua
He carried out dissections on corpses in order to understand human anatomy
In 1543 he published ‘THE FABRIC OF THE HUMAN BODY’
Vesalius disproved Galen’s anatomical drawings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

VESALIUS PUBLICATION ?

A

1543 ‘The fabric of the human body’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

WORK OF PARE ?

A

Ambroise Pare was an army surgeon
Common treatment at the time was to cauterise a wound with boiling oil to stop the bleeding

Pare discovered by chance when he ran out of oil that tying a blood vessel with silk was much more effective in stopping the bleeding
THREADS ARE CALLED LIGATURES
He put a mixture of egg yolk, rose oil and turpentine on the wound to encourage healing
In 1562 he published ‘Five books of Surgery’
Helped develop artificial limbs

Cauterisation was a popular treatment - His new method was slow to be accepted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PARE PUBLICATIONS ?

A

1562 - ‘Five books of surgery’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

WORK OF WILLIAM HARVEY ?

A

William Harvey used frogs in his experiments due to their slow heartbeats
He discovered that the heart is a PUMP and that blood is PUMPED ONE WAY in a circuit.

He disproves Galen who thought that blood was made in the liver and it replaced blood that was burned in the body

Harvey challenged the practice of bloodletting arguing the body could not have too much blood.

He discovered that blood moves away in the arteries and back in the veins - He also theorised capillaries but couldn’t prove that they existed

1628 - Published ‘On the motions of the Heart’
His work was heavily refuted as he challenged the ancient views and the popular practice of bloodletting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

HARVEY PUBLICATIONS ?

A

1628 - On the motions of the heart’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

INDUSTRIAL ADVANCES - PEOPLE ?

A

Louis Pasteur
Robert Koch
Paul Ehrlich
Dr J W Power
Bone setters of Wales

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

WORK OF LOUIS PASTEUR ?

A

Pre-Germ Theory - Spontaneous generation, belief that miasma given off by decaying material caused disease.

Louis Pasteur was a professor of chemistry at the Sorbonne
He pioneered the method of PASTEURISATION - Boiling a liquid kills harmful microbes. Process used on milk to stop it from going bad
In 1861, Pasteur published Germ Theory
Germ theory established the link between germs and disease.
Pasteur created vaccines against chicken cholera (1879) and rabies (1845)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

WORK OF KOCH AND EHRLICH ?

A

Robert Koch furthered Pasteur’s work

He identified the specific bacteria that caused different diseases
He himself identified the bacteria that caused cholera and TB
He pioneered the field of bacteriology

He discovered that the body produces antibodies that naturally kill germs and build up immunity - Proved why vaccination worked.

In 1978, identified the bacteria that caused septicaemia
Nobel prize in 1905

PAUL EHRLICH - Koch’s student, developed Salvarsan 606 - A bullet drug for targeting syphilis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

WELSH EXAMPLES - INDUSTRIAL ?

A

DR J W Power- Medical officer for Ebbw Vale
He set up courses in bacteriology to train doctors in Germ Theory
Set up the Cardiff public health laboratoryin 1898

BONE SETTERS OF WALES -
Thomas Rocyn Jones - Developed new ways of setting bones using splints

Hugh Owen Thomas - Crearted the ‘Thomas Splint’ which saved the need for many amputations during WW1.

Sir Robert Jones - First lecturer in Orthopaedic Surgery at Liverpool University

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

MODERN SCANNING TECHNIQUES - NAMES ?

A

ULTRASOUND
X-RAY
MRI
CT
PET

17
Q

WHAT IS THE BENEFIT ON SCANNING ?

A

Allows doctors to locate problems using safer non-invasive techniques

18
Q

ULTRASOUND ?

A

Using high frequency sound waves to build 3D images of internal organs
Used since the 70s for checking the development of unborn babies

19
Q

MRI ?

A

Magnetic Resonance Imaging -
Uses radio waves to build up detailed images of organs and tissue
Used to check for illness and the effectiveness of previous treatment

20
Q

PET SCANS

A

Positron Emission Tomography - Injecting a slightly radioactive tracer into the body in order to 3D colour images of tissue and bone.
Used to check for cancer and heart problems

21
Q

CT SCANS

A

Multiple X-rays taken at varying angle to produce a cross-sectional image of an area
Used to locate cancerous cells

22
Q

X-RAYS ?

A

In 1895, building on Marie Curie’s work, William Rontgen discovers that x-rays pass through the body at different rates depending on whether you hit tissue or bone.
With this information he creates the first x-ray machine
Mobile x-ray units made diagnosis quicker, it is estimated to have saved around 1M allied soldiers in WW1.
Initially high doses of ionising radiation had severe side effects

23
Q

MODERN - DNA ?

A

WATSON & CRICK discovered the exact structure of DNA in 1953, this was built heavily off of the work of ROSALIND FRANKLIN.
This explained genetic diseases like CF and Down’s Syndrome

1990 - 2003 - The Human Genome project, made a blueprint of the 100,000 genes in a human DNA molecule
Gene Therapy as a method of treating genetic disease
1996 - Dolly the Sheep

24
Q

MODERN - WELSH EXAMPLE ?

A

Martin Evans - Won the Nobel prize in 2007 for his work on stem cells and gene targeting