Knocknoit Knock In Flashcards
What does the deliberate removal or addition of a gene enable
The organisms concern to function as a model organisms for the study of genetic disease or drug therapies
What is a gene knock out
Adenocard is a transgenic organism in which a gene or jeans has been removed or made inoperative
How may genes be made inoperative?
5.4.11
Being disabled, removed or replaced with the defective of alleles.
What does this technique of gene knock out provide
5.4.11
Clues to the roles genes play in a Cell or organism
Example of a model organism for the study of genes
The mouse (knock out and knock in mouse)
What is the advantage of using a mouse
It is a mammal and biochemically and physiologically very similar to humans. It has a short life-cycle and can easily be kept in lab Tory conditions. Many people are not as ethically opposed to using mice as they would be to using larger animals.
What is gene knockin
This is where a particular gene has been added. Add a defective gene in order to study in detail disease progression
What can inactivation or replacement be used for
5.4.11
In activation or a replacement can be used to study the development of genetic disorders and drug therapies